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A8IBF5 (A8IBF5_AZOC5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818

EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818
Ordered Locus Names:AZC_3062
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP] EMBL BAF89060.1
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium

Protein attributes

Sequence length150 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00818 SAAS SAAS016856

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00818 SAAS SAAS016856

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00818 SAAS SAAS016856

Subcellular location

Cytoplasm By similarity HAMAP MF_00818 SAAS SAAS016856.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
A8IBF5 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 829A41EC2C1BEFCB

FASTA15016,867
        10         20         30         40         50         60 
MTEAKLQLGR ETALPSSPEE AVLDRVPNPH PDTNYVARFT APEFTSLCPV TGQPDFAHLV 

        70         80         90        100        110        120 
LDYVPDAWLV ESKSLKLYLA SFRNHGAFHE DCTVAIGKRL VELLKPRFFR IAGYWYPRGG 

       130        140        150 
IPIDVFWQTG ELPRGVWLPE TGVAPYRGRG 

« Hide

References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009384 Genomic DNA. Translation: BAF89060.1.
RefSeqYP_001525978.1. NC_009937.1.

3D structure databases

ProteinModelPortalA8IBF5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8IBF5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5691289.
GenomeReviewsGene locus AZC_3062 in contig AP009384_GR.
KEGGazc:AZC_3062.
PATRIC21022929. VBIAzoCau17976_3213.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG294103.
OMAHEDCTVA.
ProtClustDBPRK13258.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK09457.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF027377. Nitrile_oxidored_QueF. 1 hit.
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8IBF5_AZOC5
AccessionPrimary (citable) accession number: A8IBF5
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)