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A8I9L7 (SYR_AZOC5) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:AZC_2806
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium

Protein attributes

Sequence length586 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 586586Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000071393

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A8I9L7 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: B1AEEA880F3FBDD9

FASTA58664,361
        10         20         30         40         50         60 
MNVYAIFADH VREAVAALAG ELPEAGALDL SRIVVEPPRD AAHGDLATNA AMVLAKDLKM 

        70         80         90        100        110        120 
KPRDLAEKIA ARLAQVPNVA KVDVAGPGFI NLTLDAGYWP GVLAALLRAG TDFGRSDLGG 

       130        140        150        160        170        180 
GEAVNVEYVS ANPTGPMHVG HCRGAVFGDA LASLLAFAGF KVTREYYIND AGAQVDVLAR 

       190        200        210        220        230        240 
SAYLRYREAA TGETVEIPDG LYPGDYLVPV GKTLAEVHGS EYLESPESEW LPIFRTFAIG 

       250        260        270        280        290        300 
AMMEMIRDDL QALGISFDVF FSERSLTAAG IDRVGLTIEQ LRRTGEVYEG RLPPPKGAPI 

       310        320        330        340        350        360 
EDWEDREQSL FRSTAHGDDV DRPLVKSDGS YTYFAGDIAY HKDKFDRGFR RMIDVWGADH 

       370        380        390        400        410        420 
GGYVKRMQAA VKAVTAGQAT LDVELCQLVR LLRNGEQVRM SKRAGSFVTL REVVDEVGRD 

       430        440        450        460        470        480 
AVRFMMLFRK NDATLDFDLA KVIEQSRENP VFYVQYAHAR AQSILRNAKE QHADLPESGA 

       490        500        510        520        530        540 
IYAHAPLDRL TDEGELGLVK RLAGWPRLVE QAAHAREPHR VAFYLHEVAS EFHGQWNRGK 

       550        560        570        580 
DLPHLRFIIE NDRELTMARL ALVHGVAAVL ASGLGLLGVE AVDEMK 

« Hide

References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009384 Genomic DNA. Translation: BAF88804.1.
RefSeqYP_001525722.1. NC_009937.1.

3D structure databases

ProteinModelPortalA8I9L7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING438753.AZC_2806.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAF88804; BAF88804; AZC_2806.
GeneID5688776.
KEGGazc:AZC_2806.
PATRIC21022367. VBIAzoCau17976_2936.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMARFIMLTR.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycACAU438753:GJF3-2838-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_AZOC5
AccessionPrimary (citable) accession number: A8I9L7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 4, 2007
Last modified: April 16, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries