Reviewed, UniProtKB/Swiss-Prot A8I9L7 (SYR_AZOC5)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	AZC_2806

Organism

Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]

Taxonomic identifier

438753 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length	586 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 586	586	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_1000071393
Regions
	Motif	131 – 141	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	A8I9L7-1 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: B1AEEA880F3FBDD9	FASTA	586	64,361
	10 20 30 40 50 60 MNVYAIFADH VREAVAALAG ELPEAGALDL SRIVVEPPRD AAHGDLATNA AMVLAKDLKM 70 80 90 100 110 120 KPRDLAEKIA ARLAQVPNVA KVDVAGPGFI NLTLDAGYWP GVLAALLRAG TDFGRSDLGG 130 140 150 160 170 180 GEAVNVEYVS ANPTGPMHVG HCRGAVFGDA LASLLAFAGF KVTREYYIND AGAQVDVLAR 190 200 210 220 230 240 SAYLRYREAA TGETVEIPDG LYPGDYLVPV GKTLAEVHGS EYLESPESEW LPIFRTFAIG 250 260 270 280 290 300 AMMEMIRDDL QALGISFDVF FSERSLTAAG IDRVGLTIEQ LRRTGEVYEG RLPPPKGAPI 310 320 330 340 350 360 EDWEDREQSL FRSTAHGDDV DRPLVKSDGS YTYFAGDIAY HKDKFDRGFR RMIDVWGADH 370 380 390 400 410 420 GGYVKRMQAA VKAVTAGQAT LDVELCQLVR LLRNGEQVRM SKRAGSFVTL REVVDEVGRD 430 440 450 460 470 480 AVRFMMLFRK NDATLDFDLA KVIEQSRENP VFYVQYAHAR AQSILRNAKE QHADLPESGA 490 500 510 520 530 540 IYAHAPLDRL TDEGELGLVK RLAGWPRLVE QAAHAREPHR VAFYLHEVAS EFHGQWNRGK 550 560 570 580 DLPHLRFIIE NDRELTMARL ALVHGVAAVL ASGLGLLGVE AVDEMK

References

[1]

"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571." Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP009384 Genomic DNA. Translation: BAF88804.1.
RefSeq	YP_001525722.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5688776.
GenomeReviews	Gene locus AZC_2806 in contig AP009384_GR.
KEGG	azc:AZC_2806.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ADHHGYV.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_AZOC5

Accession

Primary (citable) accession number: A8I9L7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	December 4, 2007
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)