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A8I8A0 (A8I8A0_AZOC5) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthase HAMAP-Rule MF_00137
EC=6.3.2.6 HAMAP-Rule MF_00137
Alternative name(s):
SAICAR synthetase HAMAP-Rule MF_00137
Gene names
Name:purC HAMAP-Rule MF_00137
Ordered Locus Names:AZC_2228
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP] EMBL BAF88226.1
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium ›

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate. HAMAP-Rule MF_00137 SAAS SAAS018236

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2. HAMAP-Rule MF_00137 SAAS SAAS018236

Sequence similarities

Belongs to the SAICAR synthetase family. HAMAP-Rule MF_00137 RuleBase RU004193

Sequences

Sequence LengthMass (Da)Tools
A8I8A0 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 0133FAE074247D8A

FASTA26430,210
        10         20         30         40         50         60 
MDFLNPRYTP MSRRRRIYEG KAKVLYEGPE PGTLIQHFKD DATAFNAKKH DVIDGKGVLN 

        70         80         90        100        110        120 
NRISEYIFQR LNEIGVPTHF IRRLNMREQL IREVEIIPLE IVVRNVAAGS LSTRLGIEEG 

       130        140        150        160        170        180 
TALPRSIIEF YYKNDALNDP MVSEEHVTAF GWATTQEIDD IIALAIRVND FLTGLFLGVG 

       190        200        210        220        230        240 
IRLVDFKMEC GRLWENDMMR IVVADEISPD SCRLWDIKSN DKLDKDRFRR DLGGLVEAYS 

       250        260 
EVARRLGILT DNEPNQTKGP ALVK

« Hide

References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009384 Genomic DNA. Translation: BAF88226.1.
RefSeqYP_001525144.1. NC_009937.1.

3D structure databases

ProteinModelPortalA8I8A0.
SMRA8I8A0. Positions 12-247.
ModBaseSearch...

Protein-protein interaction databases

STRING438753.AZC_2228.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAF88226; BAF88226; AZC_2228.
GeneID5690015.
KEGGazc:AZC_2228.
PATRIC21021151. VBIAzoCau17976_2332.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0152.
HOGENOMHOG000082629.
KOK01923.
OMAVQYFKDD.
ProtClustDBPRK09362.

Enzyme and pathway databases

BioCycACAU438753:GJF3-2256-MONOMER.
UniPathwayUPA00074; UER00131.

Family and domain databases

Gene3D3.30.470.20. 1 hit.
HAMAPMF_00137. SAICAR_synth.
InterProIPR013816. ATP_grasp_subdomain_2.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
PANTHERPTHR11609. PTHR11609. 1 hit.
PfamPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsTIGR00081. purC. 1 hit.
PROSITEPS01057. SAICAR_SYNTHETASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8I8A0_AZOC5
AccessionPrimary (citable) accession number: A8I8A0
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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