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Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2UniRule annotation
Alternative name(s):
GroEL protein 2UniRule annotation
Protein Cpn60 2UniRule annotation
Gene namesi
Name:groL2UniRule annotation
Synonyms:groEL2UniRule annotation
Ordered Locus Names:AZC_2312
OrganismiAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)
Taxonomic identifieri438753 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium
Proteomesi
  • UP000000270 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003319731 – 54260 kDa chaperonin 2Add BLAST542

Proteomic databases

PRIDEiA8I5R5.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi438753.AZC_2312.

Structurei

3D structure databases

ProteinModelPortaliA8I5R5.
SMRiA8I5R5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiCVIKVGA.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

A8I5R5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKDVKFAG DAREKMLRGV DILANAVKVT LGPKGRNVVI EKSFGAPRIT
60 70 80 90 100
KDGVSVAKEI ELEDKFENLG AQLVREVASK TNDLAGDGTT TATVLAQAIV
110 120 130 140 150
KEGSKAVAAG MNPMDLKRGI DLAVDAIVKD LAAKAKKVTS NAEIAQVGTI
160 170 180 190 200
SANGDADVGK FLAEAMQKVG NEGVITVEEA KTAETELEVV EGMQFDRGYL
210 220 230 240 250
SPYFVTNAEK MRVEFEDPYI LIHEKKLSNL QELLPVLEAV VQSGKPLVIV
260 270 280 290 300
AEDVEGEALA TLVVNKLRGG LKVAAVKAPG FGDRRKAMLQ DIAILTGGQA
310 320 330 340 350
ISEDLGIKLE NVNLSMLGRA KKVVIEKENT TIVDGNGEKA DIEARVAQIK
360 370 380 390 400
AQIEETTSDY DREKLQERLA KLAGGVAVIR VGGATEVEVK EKKDRVDDAL
410 420 430 440 450
HATRAAVEEG IVPGGGVALL RAIKVLEGLK VENTDQKTGI DIVRRAIQAP
460 470 480 490 500
ARQIVANAGD DGSVVVGKIL ENETYTFGYN AQTGEYVDMV ASGIIDPAKV
510 520 530 540
VRTALQDAAS ISALIITTEA LVVELPKKAA AAPAMPGGGM DF
Length:542
Mass (Da):57,309
Last modified:December 4, 2007 - v1
Checksum:i8E98D286A997D4E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009384 Genomic DNA. Translation: BAF88310.1.
RefSeqiWP_012170839.1. NC_009937.1.

Genome annotation databases

EnsemblBacteriaiBAF88310; BAF88310; AZC_2312.
KEGGiazc:AZC_2312.

Similar proteinsi

Entry informationi

Entry nameiCH602_AZOC5
AccessioniPrimary (citable) accession number: A8I5R5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 4, 2007
Last modified: November 22, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families