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A8I541 (F16PA_AZOC5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 1
Short name=FBPase class 1
EC=3.1.3.11
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Gene names
Name:fbp
Ordered Locus Names:AZC_1811
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity. HAMAP MF_01855

Subcellular location

Cytoplasm Potential HAMAP MF_01855.

Sequence similarities

Belongs to the FBPase class 1 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 328328Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855
PRO_0000364466

Regions

Region113 – 1164Substrate binding By similarity
Region257 – 2593Substrate binding By similarity

Sites

Metal binding911Magnesium 1 By similarity
Metal binding1101Magnesium 1 By similarity
Metal binding1101Magnesium 2 By similarity
Metal binding1121Magnesium 1; via carbonyl oxygen By similarity
Metal binding1131Magnesium 2 By similarity
Metal binding2771Magnesium 2 By similarity
Binding site2051Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
A8I541 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: BFC95D8DFF666BF6

FASTA32835,195
        10         20         30         40         50         60 
MSEVTLQAFL DDWAGADPLR CAVAATVERL AEAGVSIAEL VARGPLAEDF GKVRGDEANA 

        70         80         90        100        110        120 
GGDAQKELDV IAEEELVDAL GRAPVAFLAS EESETPIPLD PHGRVVVAVD PLDGSSNIDT 

       130        140        150        160        170        180 
NVSIGTIFSI LPYDLEQHPD PAAALLQPGS AQIAAGFLVY GPATILVSSL GQGTQVFVFD 

       190        200        210        220        230        240 
HDTATFILAR EKVEIPAATK EYGINQSNVR HWAKATQRYI DDCLAGKDGP RGKDFNMRWV 

       250        260        270        280        290        300 
GSLVADAFRI FTRGGVYLYP GDSRKGYADG RLRLIYEANP IAFVTEQAGG AATDGTTRIL 

       310        320 
DIQPKQIHQR IPLVFGSREE VAHIASYY

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References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009384 Genomic DNA. Translation: BAF87809.1.
RefSeqYP_001524727.1. NC_009937.1.

3D structure databases

ProteinModelPortalA8I541.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8I541.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5691946.
GenomeReviewsGene locus AZC_1811 in contig AP009384_GR.
KEGGazc:AZC_1811.
PATRIC21020275. VBIAzoCau17976_1898.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG731261.
OMAHWEAPVQ.
ProtClustDBCLSK980045.

Enzyme and pathway databases

BioCycACAU438753:AZC_1811-MONOMER.

Family and domain databases

HAMAPMF_01855. FBPase_class1.
[Tree]
InterProIPR000146. FBPase_class-1/SBPase.
IPR020548. Fructose_bisphosphatase_AS.
[Graphical view]
KOK03841.
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PIRSFPIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF16PA_AZOC5
AccessionPrimary (citable) accession number: A8I541
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: December 4, 2007
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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