Reviewed, UniProtKB/Swiss-Prot A8I4M5 (AROC_AZOC5)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	AZC_1749

Organism

Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]

Taxonomic identifier

438753 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 371	371	Chorismate synthase HAMAP MF_00300		PRO_1000071967

Sequences

	Sequence		Length	Mass (Da)
	A8I4M5-1 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 6358A53F3F046821	FASTA	371	39,830
	10 20 30 40 50 60 MSFNTFGHLF RVTTFGESHG PAIGCVVDGC PPGLRFTVDE VQAALDRRRP GQSRFTTQRR 70 80 90 100 110 120 EPDQVRVISG TMDHPEGGLV TTGTPIGLLI ENVDQRSKDY ADIAGSYRPG HADVTYDLKY 130 140 150 160 170 180 GLRDHRGGGR SSARETAMRV AAGAIAAKVL PGVTVRAALT RIGEIEIDRA RWDWAQVSEN 190 200 210 220 230 240 PFFCPDPETV PVWTDYLDGI RKRGSSVGAV IEVVAEGVPA GLGAPIYGKL DADLAAAFMS 250 260 270 280 290 300 INAVKGVEIG EGFNAARLTG EENADEMRTG NDGRPYFLSN HAGGILGGIS SGEPVVARFA 310 320 330 340 350 360 VKPTSSILTP RRTVDKFGTE EDLITKGRHD PCVGIRAVPV GEAMMLCVLA DHLLRHRGQV 370 GTTPVWPFQR G

References

[1]

"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571." Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP009384 Genomic DNA. Translation: BAF87747.1.
RefSeq	YP_001524665.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5688189.
GenomeReviews	Gene locus AZC_1749 in contig AP009384_GR.
KEGG	azc:AZC_1749.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SRFTTQR.
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
ProDom	PD002941. Chorismate_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_AZOC5

Accession

Primary (citable) accession number: A8I4M5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	December 4, 2007
Last modified:	November 3, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)