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A8I4M5 (AROC_AZOC5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:AZC_1749
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 371371Chorismate synthase HAMAP MF_00300
PRO_1000071967

Sequences

Sequence LengthMass (Da)Tools
A8I4M5 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 6358A53F3F046821

FASTA37139,830
        10         20         30         40         50         60 
MSFNTFGHLF RVTTFGESHG PAIGCVVDGC PPGLRFTVDE VQAALDRRRP GQSRFTTQRR 

        70         80         90        100        110        120 
EPDQVRVISG TMDHPEGGLV TTGTPIGLLI ENVDQRSKDY ADIAGSYRPG HADVTYDLKY 

       130        140        150        160        170        180 
GLRDHRGGGR SSARETAMRV AAGAIAAKVL PGVTVRAALT RIGEIEIDRA RWDWAQVSEN 

       190        200        210        220        230        240 
PFFCPDPETV PVWTDYLDGI RKRGSSVGAV IEVVAEGVPA GLGAPIYGKL DADLAAAFMS 

       250        260        270        280        290        300 
INAVKGVEIG EGFNAARLTG EENADEMRTG NDGRPYFLSN HAGGILGGIS SGEPVVARFA 

       310        320        330        340        350        360 
VKPTSSILTP RRTVDKFGTE EDLITKGRHD PCVGIRAVPV GEAMMLCVLA DHLLRHRGQV 

       370 
GTTPVWPFQR G

« Hide

References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009384 Genomic DNA. Translation: BAF87747.1.
RefSeqYP_001524665.1. NC_009937.1.

3D structure databases

ProteinModelPortalA8I4M5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8I4M5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5688189.
GenomeReviewsGene locus AZC_1749 in contig AP009384_GR.
KEGGazc:AZC_1749.
PATRIC21020143. VBIAzoCau17976_1834.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG292336.
OMASRFTTQR.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycACAU438753:AZC_1749-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_AZOC5
AccessionPrimary (citable) accession number: A8I4M5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 4, 2007
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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