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A8I3B5 (RNC_AZOC5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
Ordered Locus Names:AZC_2004
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. HAMAP MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP MF_00104

Subcellular location

Cytoplasm By similarity HAMAP MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandRNA-binding
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processRNA processing

Inferred from electronic annotation. Source: InterPro

rRNA catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondouble-stranded RNA binding

Inferred from electronic annotation. Source: InterPro

ribonuclease III activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 235235Ribonuclease 3 HAMAP MF_00104
PRO_1000194406

Regions

Domain7 – 135129RNase III
Domain160 – 22970DRBM

Sequences

Sequence LengthMass (Da)Tools
A8I3B5 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 636B15BD1360DA28

FASTA23525,499
        10         20         30         40         50         60 
MSETQDFAAL EARLGHSFAD RSHLVLALTH ISSVKGQAVR VRSYQRLEFL GDHVLGSVVS 

        70         80         90        100        110        120 
HMLYAAFPKA EEGELSRRLA ELVREEACAE VAQDMGLGPY LRLGPGEAQS GARQRRAILA 

       130        140        150        160        170        180 
DVAEAVVAAV YLDGGYEAAS ALVERFWRGR LEAPRRPLRD PKTVLQEWAQ ARGLPPPVYR 

       190        200        210        220        230 
DVERSGPDHA PRFRVAVDLP GLECAEAEGG SKQTAQKAAA SAFLAREGVV TESGE 

« Hide

References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009384 Genomic DNA. Translation: BAF88002.1.
RefSeqYP_001524920.1. NC_009937.1.

3D structure databases

ProteinModelPortalA8I3B5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8I3B5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5689508.
GenomeReviewsGene locus AZC_2004 in contig AP009384_GR.
KEGGazc:AZC_2004.
PATRIC21020677. VBIAzoCau17976_2097.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG744556.
OMAALTHKSF.
ProtClustDBCLSK980124.

Enzyme and pathway databases

BioCycACAU438753:AZC_2004-MONOMER.

Family and domain databases

HAMAPMF_00104. RNase_III.
[Tree]
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like.
IPR000999. RNase_III.
IPR011907. RNase_III_bac.
[Graphical view]
Gene3DG3DSA:3.30.160.20. dsRNA-bd-like. 1 hit.
G3DSA:1.10.1520.10. RNase_III. 1 hit.
KOK03685.
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_AZOC5
AccessionPrimary (citable) accession number: A8I3B5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 4, 2007
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families