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A8I2M2 (MQO_AZOC5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:AZC_1899
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length500 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 500500Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_1000071747

Sequences

Sequence LengthMass (Da)Tools
A8I2M2 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 0B2ABC3849EEA6D2

FASTA50053,645
        10         20         30         40         50         60 
MTFSQKTDTD VLLIGAGIMS ATLGTLLHAL EPSLRLTMLE RLDDCGLESS MGWNNAGTGH 

        70         80         90        100        110        120 
AANCELNYTP QRADGSVDIS KALQVNTQFD ISRELWSHLV TTGAIPDPRA FLHPCPHMSF 

       130        140        150        160        170        180 
VWGEENVAFL KARHAAMAAH HCYHGMDYSE DPAQIAQWAP LVMEGRDPAQ KIAATRIITG 

       190        200        210        220        230        240 
TDVDYGALTH LLVGHLKTAG LDLRYNSEVI AIDRGDDGIW TVTFEDTVDG TRQQITAGFV 

       250        260        270        280        290        300 
FIGAGGAAIE LLQKSGIPEA KGYAGFPVSG IWLRCDVDAV AARHHAKVYG KAASGSPPMS 

       310        320        330        340        350        360 
VPHLDTRVIG GKTSLLFGPY AGFSTKFLKR GSLTDLFGSI TASNILPLLD VAKDNAALEE 

       370        380        390        400        410        420 
YLIGQVFQSR HHQFEMLRQF FPQARRADWQ EAVAGQRVQI IKPDQGDPGG QLEFGTELVA 

       430        440        450        460        470        480 
ASDKSLVALL GASPGASTAA AIAVHVLQTC FADRLTEDGW LPALRGALPS YGIDLITDAE 

       490        500 
ACSASRKATA KVLKIDNIDA

« Hide

References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009384 Genomic DNA. Translation: BAF87897.1.
RefSeqYP_001524815.1. NC_009937.1.

3D structure databases

ProteinModelPortalA8I2M2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8I2M2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5689767.
GenomeReviewsGene locus AZC_1899 in contig AP009384_GR.
KEGGazc:AZC_1899.
PATRIC21020459. VBIAzoCau17976_1989.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG289663.
OMANTQFEVS.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycACAU438753:AZC_1899-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_AZOC5
AccessionPrimary (citable) accession number: A8I2M2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 4, 2007
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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