A8I066 (SURE_AZOC5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	AZC_1219

Organism

Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]

Taxonomic identifier

438753 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	5'-nucleotidase surE HAMAP MF_00060		PRO_1000071158
Sites
	Metal binding	8	1	Divalent metal cation By similarity
	Metal binding	9	1	Divalent metal cation By similarity
	Metal binding	40	1	Divalent metal cation By similarity
	Metal binding	93	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8I066 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: D716252BE6D9D236	FASTA	255	27,526
	10 20 30 40 50 60 MRILVTNDDG IHAPGLDACA RIAAALSDDV WVVAPETDQS GVAHSLSLND PLRLRKVAAQ 70 80 90 100 110 120 RYAVKGTPTD CVIMAVRHVL IDNPPDLILS GVNRGQNIAE DVSYSGTVAG AIEGTILGIP 130 140 150 160 170 180 SIALSQAFGP QTRDNPSYQT AETHGPDVIR TLLAEGIPAG VLINVNFPDR TPDQVAGIAV 190 200 210 220 230 240 TAQGRRDQKL MRIDPRKDGR GNDYFWIAFE RRSADTVPGS DLRALDEGRI SVTPLRVEQT 250 DEPMMTRLAQ VFEAR

References

[1]

"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571." Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009384 Genomic DNA. Translation: BAF87217.1.
RefSeq	YP_001524135.1. NC_009937.1.
3D structure databases
ProteinModelPortal	A8I066.
ModBase	Search...
Protein-protein interaction databases
STRING	A8I066.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5692230.
GenomeReviews	Gene locus AZC_1219 in contig AP009384_GR.
KEGG	azc:AZC_1219.
PATRIC	21019013. VBIAzoCau17976_1276.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG600532.
OMA	EVWTVAP.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	ACAU438753:AZC_1219-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_AZOC5

Accession

Primary (citable) accession number: A8I066

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	December 4, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program