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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei158 – 1581UniRule annotation
Active sitei593 – 5931UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciACAU438753:GJF3-4734-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:AZC_4669
OrganismiAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
Taxonomic identifieri438753 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium
ProteomesiUP000000270: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 931931Phosphoenolpyruvate carboxylasePRO_1000072621Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi438753.AZC_4669.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8I060-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSAVWAVVS EQEAGGPDKD QPLRDDIRLL GRILGDTVRE QEGDAIYELV
60 70 80 90 100
ETIRQTSIRF HRDADEAARQ ELNALLESMT PEVAVQIIRA FSYFSHLANI
110 120 130 140 150
AEDQHHSRRN RAHAVAGSAP RPGTLANALA RAEKAGIGAA ELRAFFDAAL
160 170 180 190 200
VSPVLTAHPT EVRRKSTMNR EMEIADLLDL KERLQATPQE AREQDEKLRR
210 220 230 240 250
AVLTLWQTAL LRKFKLTVLD EVQNGLSYYD YTFLAEVPRL LCALEDHLAE
260 270 280 290 300
QEGGEPGAEL PPFLRIGSWI GGDRDGNPFV TADVLRETVR QHRDRVMAFY
310 320 330 340 350
LEQVGLLVTE LSLAKRLVAV SEDLTALAER SGDRAPEHRE EPYRLALVGI
360 370 380 390 400
HNRLKATVAA QKAADDGKTM GAAEDGHLPY PDAAAFRADL DILYRSLMAN
410 420 430 440 450
GSAILARGRL RHVRRAVDSF GFHLASLDLR QNSDVHERTV ADLLEQAAPG
460 470 480 490 500
TNYHALDEEA RIAVLRAELT NPRPLASPFL SYTEETRSEL AILRTAAEAH
510 520 530 540 550
ARLGKTVIPN AIISKAEGIS DMLELALLLK EVGLVSATGE SAINVIPLFE
560 570 580 590 600
TIGDLQACGP VMDRLLALPE YRALVDSRGG EQEVMLGYSD SNKDGGFVSS
610 620 630 640 650
GWELYKAEIA LIEVFARHKV KLRLFHGRGG SVGRGGGPSY DAILAQPAGA
660 670 680 690 700
VSGQIRITEQ GEIISSKYSN PENGRRNLEI LVSATLESTL LEAEQASPRP
710 720 730 740 750
EFLAAMEELS KTAFTAYRSL VYETPGFEDY FWSSTVISEI ATLNIGSRPA
760 770 780 790 800
SRNKTRAIEA LRAIPWVFSW SQCRLMLPGW YGFGTAIAAF VEARPVDGIA
810 820 830 840 850
FLQSMYREWP FFRTLLSNMD MVLSKSSLAV ASRYAELVPD EELRTRIFSR
860 870 880 890 900
ISAEYQSAIT SLLAIMGQKK LLEANPLLDR SIRNRFPYLD PLNHIQVELL
910 920 930
KLHRSDAGSD HVLHGIQLTI NGISAGLRNS G
Length:931
Mass (Da):102,788
Last modified:December 4, 2007 - v1
Checksum:i94A775227B24E960
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009384 Genomic DNA. Translation: BAF90667.1.
RefSeqiWP_012173188.1. NC_009937.1.
YP_001527585.1. NC_009937.1.

Genome annotation databases

EnsemblBacteriaiBAF90667; BAF90667; AZC_4669.
GeneIDi5688301.
KEGGiazc:AZC_4669.
PATRICi21026287. VBIAzoCau17976_4866.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009384 Genomic DNA. Translation: BAF90667.1.
RefSeqiWP_012173188.1. NC_009937.1.
YP_001527585.1. NC_009937.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi438753.AZC_4669.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAF90667; BAF90667; AZC_4669.
GeneIDi5688301.
KEGGiazc:AZC_4669.
PATRICi21026287. VBIAzoCau17976_4866.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciACAU438753:GJF3-4734-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
    Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43989 / DSM 5975 / ORS 571.

Entry informationi

Entry nameiCAPP_AZOC5
AccessioniPrimary (citable) accession number: A8I060
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 4, 2007
Last modified: March 4, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.