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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei142GTPUniRule annotation1
Binding sitei146GTPUniRule annotation1
Binding sitei190GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi111 – 113GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:AZC_4564Imported
OrganismiAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)Imported
Taxonomic identifieri438753 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium
Proteomesi
  • UP000000270 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi438753.AZC_4564.

Structurei

3D structure databases

ProteinModelPortaliA8HZB7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 208TubulinInterPro annotationAdd BLAST193
Domaini210 – 328Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiRAVMREM.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR017844. Cell_div_FtsZ_C.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
TIGR03483. FtsZ_alphas_C. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A8HZB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSINLQMPDI RELRPRITVF GCGGAGGNAV NNMISAGLSG VEFVVANTDA
60 70 80 90 100
QALSLSKADR LVQMGVAVTE GLGAGSQPEV GRAAAEEVID EIRDHLSGSH
110 120 130 140 150
MVFITAGMGG GTGTGAAPVV ARAARELGIL TVGVVTKPFH FEGQRRMRVA
160 170 180 190 200
EHGINELQKT VDTLIVIPNQ NLFRVANEKT TFADAFAMAD QVLYSGVACI
210 220 230 240 250
TDLMVKEGLI NLDFADVRAV MRDMGKAMMG TGEASGDKRA LQAAEAAIAN
260 270 280 290 300
PLLDEISMRG AGGLLISITG GNDMTLFEVD EAATRIREEV DPDANIILGA
310 320 330 340 350
TFDQSLDGII RVSVVATGID PAVVPEQIQT STTLGEFQGR KMSNAGRAAV
360 370 380 390 400
EQAREAQIRS AVASISAEDL MDLEPAAPPA PPVAQQPLPQ PTAYREPAPQ
410 420 430 440 450
QAPAPQPAPR QSFPERTTQP AQVVDEVTIR AATPKPSFFV EPEQPPAPPP
460 470 480 490 500
VVEDEFAPYI PPQTQRPRAP RMPRVDELPV PAQNQIRAQR GEAPVEQKRM
510 520 530 540 550
TLLQRLASVG GLGRSHDEPE APPARREQPS MRAPEPRGAD PRMGGRPGDP
560 570 580 590
VSEFAKRPAT RPQAEVPSRQ APQQGHDDDQ LDIPAFLRRQ AN
Length:592
Mass (Da):63,107
Last modified:December 4, 2007 - v1
Checksum:iC276BD209739AAE1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009384 Genomic DNA. Translation: BAF90562.1.
RefSeqiWP_012173083.1. NC_009937.1.

Genome annotation databases

EnsemblBacteriaiBAF90562; BAF90562; AZC_4564.
KEGGiazc:AZC_4564.

Similar proteinsi

Entry informationi

Entry nameiA8HZB7_AZOC5
AccessioniPrimary (citable) accession number: A8HZB7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: September 27, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported