Reviewed, UniProtKB/Swiss-Prot A8HXJ6 (PSD_AZOC5)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Ordered Locus Names:	AZC_1509

Organism

Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]

Taxonomic identifier

438753 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664
Cofactor	Pyruvoyl group By similarity.
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphatidylethanolamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Phosphatidylserine decarboxylase beta chain By similarity		PRO_1000072714
	Chain	190 – 233	44	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_1000072715
Sites
	Site	189 – 190	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	190	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8HXJ6-1 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: FA6BB2D6DD8143D4	FASTA	233	25,161
	10 20 30 40 50 60 MSVLTSIRKS LVPIHREGYP FIAIAVVIAI GLLSVSTFFG MLAVGLAIWT ALFFRDPQRV 70 80 90 100 110 120 TPLREGLVVA PADGRISQIG LALPPRELGL SEVPLLRISI FMNVFNVHVN RAPVTGRIEK 130 140 150 160 170 180 IAYKPGLFLN AELDKASEDN ERNGLIIHGP NGVVGVVQIA GLIARRIVSF VHEGETIGAG 190 200 210 220 230 ERFGLIRFGS RVDVYLPVGT RVLVSEGQLT VAGETILADY DAAPTRDIAF RVS

References

[1]

"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571." Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP009384 Genomic DNA. Translation: BAF87507.1.
RefSeq	YP_001524425.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5690075.
GenomeReviews	Gene locus AZC_1509 in contig AP009384_GR.
KEGG	azc:AZC_1509.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	DKASEDN.
Family and domain databases
HAMAP	MF_00664. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR004428. PtdSer_deCO2ase_related. [Graphical view]
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00164. PS_decarb_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_AZOC5

Accession

Primary (citable) accession number: A8HXJ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	December 4, 2007
Last modified:	November 3, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)