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A8HXJ6 (PSD_AZOC5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:AZC_1509
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 189189Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000072714
Chain190 – 23344Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000072715

Sites

Site189 – 1902Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1901Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
A8HXJ6 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: FA6BB2D6DD8143D4

FASTA23325,161
        10         20         30         40         50         60 
MSVLTSIRKS LVPIHREGYP FIAIAVVIAI GLLSVSTFFG MLAVGLAIWT ALFFRDPQRV 

        70         80         90        100        110        120 
TPLREGLVVA PADGRISQIG LALPPRELGL SEVPLLRISI FMNVFNVHVN RAPVTGRIEK 

       130        140        150        160        170        180 
IAYKPGLFLN AELDKASEDN ERNGLIIHGP NGVVGVVQIA GLIARRIVSF VHEGETIGAG 

       190        200        210        220        230 
ERFGLIRFGS RVDVYLPVGT RVLVSEGQLT VAGETILADY DAAPTRDIAF RVS

« Hide

References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009384 Genomic DNA. Translation: BAF87507.1.
RefSeqYP_001524425.1. NC_009937.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA8HXJ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5690075.
GenomeReviewsGene locus AZC_1509 in contig AP009384_GR.
KEGGazc:AZC_1509.
PATRIC21019611. VBIAzoCau17976_1573.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG541103.
OMAIFMSVFN.
ProtClustDBCLSK980372.

Enzyme and pathway databases

BioCycACAU438753:AZC_1509-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_AZOC5
AccessionPrimary (citable) accession number: A8HXJ6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 4, 2007
Last modified: January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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