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A8HV58 (A8HV58_AZOC5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:AZC_4272
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP] EMBL BAF90270.1
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2221Iron By similarity HAMAP MF_00323
Metal binding3031Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A8HV58 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: BD58F9474D8F4E2E

FASTA35440,175
        10         20         30         40         50         60 
MTVTTAPAFG DTRHFPAEHP RVNYGRIGVL LVNLGTPEAT DYWSMRRYLK EFLSDTRVIE 

        70         80         90        100        110        120 
TNRALWWVIL NGIILTVRPG PKGRDYETIW NKERNEGPLK TITRGQSEKL GAMIADRDPR 

       130        140        150        160        170        180 
IVVDWAMRYG KPPIAERLDA LQKQGCERIL IVPMYPQYAA ATSATVCDKA FDALKKMRWQ 

       190        200        210        220        230        240 
PFIRIAPNWH DDPVYIDALA TSLEGHLKGL DFEPEVILAS YHGVPKSYLM KGDPYHCQCL 

       250        260        270        280        290        300 
KTTRLLRDRL GMSEEKLRTT FQSRFGNEEW LQPYTDKTVE ALARGGVKRI AVLNPGFTAD 

       310        320        330        340        350 
CLETLEEIGG ENAEIFHLHG GEKFAAIPCL NDTDEGMRVI ENVVRRELSG WIAA

« Hide

References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009384 Genomic DNA. Translation: BAF90270.1.
RefSeqYP_001527188.1. NC_009937.1.

3D structure databases

ProteinModelPortalA8HV58.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8HV58.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5688040.
GenomeReviewsGene locus AZC_4272 in contig AP009384_GR.
KEGGazc:AZC_4272.
PATRIC21025457. VBIAzoCau17976_4457.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697135.
OMAIRPAKSA.
ProtClustDBCLSK2459219.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8HV58_AZOC5
AccessionPrimary (citable) accession number: A8HV58
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info