Reviewed, UniProtKB/Swiss-Prot A8HUR7 (GLMM_AZOC5)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	AZC_0975

Organism

Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]

Taxonomic identifier

438753 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Phosphoglucosamine mutase HAMAP MF_01554		PRO_1000073569
Sites
	Active site	101	1	Phosphoserine intermediate By similarity
	Metal binding	101	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
Amino acid modifications
	Modified residue	101	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8HUR7-1 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 7750C3E539B19C1A	FASTA	447	48,485
	10 20 30 40 50 60 MARKYFGTDG VRGRANATLT ADLALRVGMA AGLAFRRGEH RHRVVIGKDT RLSGYMIENA 70 80 90 100 110 120 LVAGFTSVGM DVLLLGPMPT PAVGMLTRSM RADLGVMISA SHNPFDDNGI KLFGPDGFKL 130 140 150 160 170 180 SDQIEHEIEE LIDEDLSKKL AQPMDIGRAR RVEGVHARYI EYAKRTLPRD QSFEGLRVVV 190 200 210 220 230 240 DCANGAAYRV APDALWELGA EVISMGVEPD GLNINRDVGS TSPAALSAKV REVRADVGIA 250 260 270 280 290 300 LDGDADRVII VDEKGHVVDG DQIMAVVAHS FKEDGRLSRD GIVATVMSNL GLERYLKDEG 310 320 330 340 350 360 LTLARTSVGD RYVLERMRSD GYNVGGEQSG HIILSDYSTT GDGLLAALQV LAVVARSERP 370 380 390 400 410 420 VSEVCHRFDP LPQVLKNVRY SSGKPLEHEN VQSAIADAER RLANHGRLLI RPSGTEPVIR 430 440 VMGEGDDFEL VEGVVDEVIE ALRKVAA

References

[1]

"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571." Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP009384 Genomic DNA. Translation: BAF86973.1.
RefSeq	YP_001523891.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5690551.
GenomeReviews	Gene locus AZC_0975 in contig AP009384_GR.
KEGG	azc:AZC_0975.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	STHPEAM.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_AZOC5

Accession

Primary (citable) accession number: A8HUR7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	December 4, 2007
Last modified:	November 3, 2009
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)