ID   GCSPA_AZOC5             Reviewed;         447 AA.
AC   A8HT29;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   16-JUN-2009, entry version 11.
DE   RecName: Full=Probable glycine dehydrogenase [decarboxylating] subunit 1;
DE            EC=1.4.4.2;
DE   AltName: Full=Glycine decarboxylase subunit 1;
DE   AltName: Full=Glycine cleavage system P-protein subunit 1;
GN   Name=gcvPA; OrderedLocusNames=AZC_4248;
OS   Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Xanthobacteraceae; Azorhizobium.
OX   NCBI_TaxID=438753;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T.,
RA   Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B.,
RA   Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M.,
RA   Oyaizu H.;
RT   "Complete genome sequence of the nitrogen-fixing bacterium
RT   Azorhizobium caulinodans ORS571.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The glycine cleavage system catalyzes the degradation of
CC       glycine. The P protein binds the alpha-amino group of glycine
CC       through its pyridoxal phosphate cofactor; CO(2) is released and
CC       the remaining methylamine moiety is then transferred to the
CC       lipoamide cofactor of the H protein (By similarity).
CC   -!- CATALYTIC ACTIVITY: Glycine + H-protein-lipoyllysine = H-protein-
CC       S-aminomethyldihydrolipoyllysine + CO(2).
CC   -!- SUBUNIT: The glycine cleavage system is composed of four proteins:
CC       P, T, L and H. In this organism, the P 'protein' is an heterodimer
CC       of two subunits (By similarity).
CC   -!- SIMILARITY: Belongs to the gcvP family. N-terminal subunit
CC       subfamily.
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DR   EMBL; AP009384; BAF90246.1; -; Genomic_DNA.
DR   RefSeq; YP_001527164.1; -.
DR   GeneID; 5691343; -.
DR   GenomeReviews; AP009384_GR; AZC_4248.
DR   KEGG; azc:AZC_4248; -.
DR   OMA; A8HT29; VANASMY.
DR   GO; GO:0004375; F:glycine dehydrogenase (decarboxylating) act...; IEA:EC.
DR   GO; GO:0019464; P:glycine decarboxylation via glycine cleavag...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00712; -; 1.
DR   InterPro; IPR003437; GDC-P.
DR   PANTHER; PTHR11773; GDC-P; 1.
DR   Pfam; PF02347; GDC-P; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Oxidoreductase.
FT   CHAIN         1    447       Probable glycine dehydrogenase
FT                                [decarboxylating] subunit 1.
FT                                /FTId=PRO_1000072767.
SQ   SEQUENCE   447 AA;  47277 MW;  D776DEC3602BF231 CRC64;
     MRYLPLTPED RTEMLARIGA PSVDALFADI PAAKLDPALA DLPAHKTELS VERTLGALSA
     QNVPAGSVPF FVGAGAYRHH VPATVDHLIQ RSEFLTSYTP YQPEIAQGTL QYLFEFQTQV
     GELTGMEVAN ASMYDGSTAA AEAVLMAHRV TKRRKAVVAG NVHPHYRETI ATLSLYADDA
     VVALSPVPQG GEDILSAIDG ETSCVVVQSP DVFGNIVDLK PIAEKAHAAG ALLIAVFTEV
     VSLGLIEPPG AQGADIVVGE GQSIGNPLTF GGPYVGLFAT RQKYVRQMPG RLAGETVDAS
     GKRGFVLTLS TREQHIRREK ATSNICTNSG LCALAFTIHL TLLGETGLRK LARLNHANAC
     KLADKLAAVP GVQVLNSAFF NEFTLRVPGK AVDVIEKLAA KGVLGGVPYA RLAPKAGLDD
     LILVAATEIN TDEDRAAYAA ALKEVLA
//