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Protein

Protein-S-isoprenylcysteine O-methyltransferase

Gene

CHLREDRAFT_146308

Organism
Chlamydomonas reinhardtii (Chlamydomonas smithii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Divalent metal cations. Probably Zn2+.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseUniRule annotation, Transferase
LigandS-adenosyl-L-methionineUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-S-isoprenylcysteine O-methyltransferaseUniRule annotation (EC:2.1.1.100UniRule annotation)
Gene namesi
ORF Names:CHLREDRAFT_146308Imported
OrganismiChlamydomonas reinhardtii (Chlamydomonas smithii)
Taxonomic identifieri3055 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaChlorophyceaeChlamydomonadalesChlamydomonadaceaeChlamydomonas

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei98 – 123HelicalUniRule annotationAdd BLAST26

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiA8HPP9

Interactioni

Protein-protein interaction databases

STRINGi3055.EDP09673

Family & Domainsi

Sequence similaritiesi

Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2628 Eukaryota
COG2020 LUCA
InParanoidiA8HPP9
KOiK00587

Family and domain databases

InterProiView protein in InterPro
IPR007269 ICMT_MeTrfase
IPR025770 PPMT_MeTrfase
PfamiView protein in Pfam
PF04140 ICMT, 1 hit
PROSITEiView protein in PROSITE
PS51564 SAM_ICMT, 1 hit

Sequencei

Sequence statusi: Complete.

A8HPP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRHELSWNSW LFSRPYTVAM GFAILEYSVE ALLVPGLKGY LPWLGVVLIV
60 70 80 90 100
LGEGIRKVGM LTAQSNFTHN IRVRRDERHA LVTHGIYRYV RHPGYLGWYI
110 120 130 140 150
WCVGTQVLLC NPFSIVAFAI VAWRFFRERI EYEEYYLRRF FGYQYEAYAA
160
RTPTWLPFIP
Length:160
Mass (Da):18,963
Last modified:December 4, 2007 - v1
Checksum:iC5AE1C5F1C9AF8B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS496108 Genomic DNA Translation: EDP09673.1
RefSeqiXP_001689935.1, XM_001689883.1

Genome annotation databases

EnsemblPlantsiEDP09673; EDP09673; CHLREDRAFT_146308
GeneIDi5715155
GrameneiEDP09673; EDP09673; CHLREDRAFT_146308
KEGGicre:CHLREDRAFT_146308

Entry informationi

Entry nameiA8HPP9_CHLRE
AccessioniPrimary (citable) accession number: A8HPP9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: April 25, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)