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A8HA69 (RLMF_SHEPA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA large subunit methyltransferase F
EC=2.1.1.181
Alternative name(s):
23S rRNA mA1618 methyltransferase
rRNA adenine N-6-methyltransferase
Gene names
Name:rlmF
Ordered Locus Names:Spea_4146
OrganismShewanella pealeana (strain ATCC 700345 / ANG-SQ1) [Complete proteome] [HAMAP]
Taxonomic identifier398579 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length380 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the adenine in position 1618 of 23S rRNA By similarity. HAMAP MF_01848

Catalytic activity

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA. HAMAP MF_01848

Subcellular location

Cytoplasm Potential HAMAP MF_01848.

Sequence similarities

Belongs to the methyltransferase superfamily. METTL16/rlmF family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionrRNA (adenine-N6-)-methyltransferase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 380380Ribosomal RNA large subunit methyltransferase F HAMAP MF_01848
PRO_0000349959

Sequences

Sequence LengthMass (Da)Tools
A8HA69 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 9477D5128A7456CE

FASTA38041,953
        10         20         30         40         50         60 
MSHKTKSTTQ ERKAGKSSAP QRQVVSKSSL QKKVSKPTAT AKLQKSKALH PRNAHNNGYD 

        70         80         90        100        110        120 
FAALVTAFPK LKAFVKPNPY GNLSIDFADP VAVKMLNAAL LKFHYGVGHW DIPDGFLCPP 

       130        140        150        160        170        180 
IPGRADYIHH VADLLAVKKS SKKRIPKGPK VRVLDIGTGA NVIYPLLGIQ SYGWDFVGSD 

       190        200        210        220        230        240 
VDPLSIANAQ QIFAGNSDIA NKFSSRLQAD SKHVFHGVIE ANERFDLTLC NPPFHASLAE 

       250        260        270        280        290        300 
ASEGTARKLK NLAANRAKSS QVMSPQVQPS GKVKPATDKN HGVLNFGGQK AELWCEGGEL 

       310        320        330        340        350        360 
QFLRTMIEES HDFASQCLWF TTLVSKKENL NPAKALLAKI KAEEVKEIEM HQGNKITRVL 

       370        380 
AWTFLKPEQR ELWVQYRDAQ

« Hide

References

[1]"Complete sequence of Shewanella pealeana ATCC 700345."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Zhao J.-S.Z., Manno D., Hawari J., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700345 / ANG-SQ1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000851 Genomic DNA. Translation: ABV89456.1.
RefSeqYP_001503991.1. NC_009901.1.

3D structure databases

ProteinModelPortalA8HA69.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8HA69.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5664530.
GenomeReviewsGene locus Spea_4146 in contig CP000851_GR.
KEGGspl:Spea_4146.
NMPDRfig|398579.3.peg.3600.
PATRIC23538539. VBIShePea72822_4336.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3129.
HOGENOMHBG747880.
OMAWSFVGSD.
ProtClustDBPRK11727.

Enzyme and pathway databases

BioCycSPEA398579:SPEA_4146-MONOMER.

Family and domain databases

HAMAPMF_01848. 23SrRNA_methyltr_F.
[Tree]
InterProIPR016909. rRNA_lsu_methyltransferase_F.
IPR010286. SAM-Mtase_prd.
[Graphical view]
KOK06970.
PANTHERPTHR13393. DUF890. 1 hit.
PfamPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFPIRSF029038. Mtase_YbiN_prd. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRLMF_SHEPA
AccessionPrimary (citable) accession number: A8HA69
Entry history
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: November 13, 2007
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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