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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:Spea_4146
OrganismiShewanella pealeana (strain ATCC 700345 / ANG-SQ1)
Taxonomic identifieri398579 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000002608 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003499591 – 380Ribosomal RNA large subunit methyltransferase FAdd BLAST380

Interactioni

Protein-protein interaction databases

STRINGi398579.Spea_4146.

Structurei

3D structure databases

ProteinModelPortaliA8HA69.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiPOG091H05H4.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F. 1 hit.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 2 hits.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 2 hits.

Sequencei

Sequence statusi: Complete.

A8HA69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHKTKSTTQ ERKAGKSSAP QRQVVSKSSL QKKVSKPTAT AKLQKSKALH
60 70 80 90 100
PRNAHNNGYD FAALVTAFPK LKAFVKPNPY GNLSIDFADP VAVKMLNAAL
110 120 130 140 150
LKFHYGVGHW DIPDGFLCPP IPGRADYIHH VADLLAVKKS SKKRIPKGPK
160 170 180 190 200
VRVLDIGTGA NVIYPLLGIQ SYGWDFVGSD VDPLSIANAQ QIFAGNSDIA
210 220 230 240 250
NKFSSRLQAD SKHVFHGVIE ANERFDLTLC NPPFHASLAE ASEGTARKLK
260 270 280 290 300
NLAANRAKSS QVMSPQVQPS GKVKPATDKN HGVLNFGGQK AELWCEGGEL
310 320 330 340 350
QFLRTMIEES HDFASQCLWF TTLVSKKENL NPAKALLAKI KAEEVKEIEM
360 370 380
HQGNKITRVL AWTFLKPEQR ELWVQYRDAQ
Length:380
Mass (Da):41,953
Last modified:November 13, 2007 - v1
Checksum:i9477D5128A7456CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000851 Genomic DNA. Translation: ABV89456.1.
RefSeqiWP_012157334.1. NC_009901.1.

Genome annotation databases

EnsemblBacteriaiABV89456; ABV89456; Spea_4146.
KEGGispl:Spea_4146.
PATRICi23538539. VBIShePea72822_4336.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000851 Genomic DNA. Translation: ABV89456.1.
RefSeqiWP_012157334.1. NC_009901.1.

3D structure databases

ProteinModelPortaliA8HA69.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi398579.Spea_4146.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV89456; ABV89456; Spea_4146.
KEGGispl:Spea_4146.
PATRICi23538539. VBIShePea72822_4336.

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiPOG091H05H4.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F. 1 hit.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 2 hits.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiRLMF_SHEPA
AccessioniPrimary (citable) accession number: A8HA69
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: November 13, 2007
Last modified: November 2, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.