Reviewed, UniProtKB/Swiss-Prot A8H786 (RLMG_SHEPA)

Names and origin

Protein names

Recommended name:
    Ribosomal RNA large subunit methyltransferase G
    EC=2.1.1.52
Alternative name(s):
    rRNA (guanine-N(2)-)-methyltransferase rlmG
    23S rRNA m2G1835 methyltransferase

Gene names

Name:	rlmG
Ordered Locus Names:	Spea_3107

Organism

Shewanella pealeana (strain ATCC 700345 / ANG-SQ1) [Complete proteome] [HAMAP]

Taxonomic identifier

398579 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	413 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity.
Catalytic activity	S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N(2)-methylguanine. HAMAP MF_01859
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 413	413	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366513

Sequences

	Sequence		Length	Mass (Da)
	A8H786-1 [UniParc]. Last modified March 24, 2009. Version 2. Checksum: 8269BA2EA8FCBE94	FASTA	413	45,683
	10 20 30 40 50 60 MTTQFSVSGI ELELFRYPSR QESNLQAWDA ADEHLIKHLI DTEQTSISTA VVNDGFGALT 70 80 90 100 110 120 AGLLSINPSW PLTLETDAKT SQLGTSQNLT RNQLSQESIT WVNSRDELPQ VIELVLMKLP 130 140 150 160 170 180 KNLNYFSHQL NRLSHVLPAG TQVLIGAKAK SINKSLLETI EKNLGPASAS LTWKKTRVIT 190 200 210 220 230 240 CIADGKARAL PKATTWSVPE FKLQISNLSN VFAANKLDIG ARIMLDNMPK GDYKSIVDLG 250 260 270 280 290 300 CGNGILGLHA KQVFPEAYIH FIDDSEMAVA SARENWALNK LDNPALVGEQ ATFGWDDCLT 310 320 330 340 350 360 NMSEGFRPDL VLCNPPFHQG EAITDHIAWQ MFLDAFRRLK NGGILHVVGN RHLAYHVKLQ 370 380 390 400 410 RIFKNCTTVA SNGKFVILQA QKISKKAQEA EVEQAFDTET PHPQSALYGK PKA

References

[1]

"Complete sequence of Shewanella pealeana ATCC 700345." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Zhao J.-S.Z., Manno D., Hawari J., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000851 Genomic DNA. Translation: ABV88423.1. Different initiation.
RefSeq	YP_001502958.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A8H786.
Genome annotation databases
GeneID	5663496.
GenomeReviews	Gene locus Spea_3107 in contig CP000851_GR.
KEGG	spl:Spea_3107.
NMPDR	fig|398579.3.peg.2691.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_01859. [Tree]
InterPro	IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_SHEPA

Accession

Primary (citable) accession number: A8H786

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	March 24, 2009
Last modified:	September 1, 2009
This is version 15 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)