A8GVX5 (A8GVX5_RICB8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163

Gene names

Name:	def EMBL ABV79002.1
Synonyms:	def1 HAMAP MF_00163
Ordered Locus Names:	A1I_03205

Organism

Rickettsia bellii (strain OSU 85-389) [Complete proteome] [HAMAP] EMBL ABV79002.1

Taxonomic identifier

391896 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia

Protein attributes

Sequence length	175 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. HAMAP MF_00163

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00163 SAAS SAAS000181
Ligand	Iron HAMAP MF_00163 Metal-binding HAMAP MF_00163 SAAS SAAS000181
Molecular function	Hydrolase HAMAP MF_00163 SAAS SAAS000181 EMBL ABV79002.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	142	1	By similarity HAMAP MF_00163
	Metal binding	99	1	Iron By similarity HAMAP MF_00163
	Metal binding	141	1	Iron By similarity HAMAP MF_00163
	Metal binding	145	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	A8GVX5 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 9DAE14AE7151BE7F	FASTA	175	20,456
	10 20 30 40 50 60 MSILPIVTVP DERLKQKSQA VLEVNNQIRK FMDDMVETMY HEDGGGLAAV QVGVLKRIMV 70 80 90 100 110 120 IDIKDHDPIK RPKDFYPLFI VNPEIIEKSE ELVIANEGCI SVPEQRYEIA RSESIKIRYL 130 140 150 160 170 DYHNKPQELE ANDWLARVIQ HEYDHLEGKL MIDYLSSMKR NIALRKLRKL KKNIV

References

[1]	"Complete genome sequencing of Rickettsia bellii." Madan A., Lee H., Madan A., Yoon J.-G., Ryu G.-Y., Dasch G., Ereemeva M. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: OSU 85-389 EMBL ABV79002.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000849 Genomic DNA. Translation: ABV79002.1.
RefSeq	YP_001496039.1. NC_009883.1.
3D structure databases
ProteinModelPortal	A8GVX5.
ModBase	Search...
Protein-protein interaction databases
STRING	A8GVX5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5646551.
GenomeReviews	Gene locus A1I_03205 in contig CP000849_GR.
KEGG	rbo:A1I_03205.
PATRIC	17879196. VBIRicBel35792_0669.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0242.
HOGENOM	HBG665227.
OMA	ETMIASE.
ProtClustDB	PRK00150.
Enzyme and pathway databases
BioCyc	RBEL391896:A1I_03205-MONOMER.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8GVX5_RICB8

Accession

Primary (citable) accession number: A8GVX5

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)