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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Rickettsia bellii (strain OSU 85-389)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciRBEL391896:G1GA6-519-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:A1I_02595
OrganismiRickettsia bellii (strain OSU 85-389)
Taxonomic identifieri391896 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000106411 – 185Peptidyl-tRNA hydrolaseAdd BLAST185

Proteomic databases

PRIDEiA8GVL6

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA8GVL6
SMRiA8GVL6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

A8GVL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMLIIGLGNP GKEYEHTRHN IGFIALENIA KQYETSFSVK KKFHCEIAES
60 70 80 90 100
TNNGQKLIFV KPTTYMNLSG KSVIAVKTYY NIPLEKIFVI HDDIDLELGK
110 120 130 140 150
IKFKTGGGNG GHNGLKSIDG IIENNYHRIR IGVGRPQNSQ DVADYVLNNF
160 170 180
SKTEYVIAEQ AIDKITDNFN LILENKLEEF KSKMV
Length:185
Mass (Da):20,912
Last modified:November 13, 2007 - v1
Checksum:iA49871363AA96081
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000849 Genomic DNA Translation: ABV78893.1
RefSeqiWP_012151719.1, NC_009883.1

Genome annotation databases

EnsemblBacteriaiABV78893; ABV78893; A1I_02595
KEGGirbo:A1I_02595

Similar proteinsi

Entry informationi

Entry nameiPTH_RICB8
AccessioniPrimary (citable) accession number: A8GVL6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 13, 2007
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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