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Protein
Submitted name:

Alpha-ketoglutarate decarboxylase

Gene

kgd

Organism
Rickettsia bellii (strain OSU 85-389)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciRBEL391896:GH75-345-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-ketoglutarate decarboxylaseImported (EC:1.2.4.2Imported)
Gene namesi
Name:kgdImported
Ordered Locus Names:A1I_01830Imported
OrganismiRickettsia bellii (strain OSU 85-389)Imported
Taxonomic identifieri391896 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group
ProteomesiUP000001152: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi391896.A1I_01830.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiEHSNARP.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

A8GV81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEENLKKTGF LFGGNAVFIE ELYKQYLENP ASVDQTWQEF FSSVKDSNQL
60 70 80 90 100
LNKSTAKIIL KAAATEESKT SENPVSTTNN FNVGAMIKNY RKYAHYLAKL
110 120 130 140 150
DPLGLEVTKT KEDLKLSIEN FGFTNDHLSK VIEHKFLEKT YNLGELVNFL
160 170 180 190 200
DKTYAGSIGV EFEQVENAEE KNWLYSKLES GVISFSSEEK KNILNDLVEV
210 220 230 240 250
EGFEQYLHTK FPGAKRFSVE GGDASIVAMN KAIDLSLHQG VEEIVIGMAH
260 270 280 290 300
RGRLNTLTKV VGKPYRAVIA GFISGSVFPD ELNVSGDVKY HLGYSSDRVV
310 320 330 340 350
GDKKIHLSLA DNPSHLEAVN PIFAGKVRAK QDMLKDNKRS KVKAILVHGD
360 370 380 390 400
AAFCGQGVVA ESLSMSPLAA YNIGGVLHFV INNQLGFTAN AADTRASRYS
410 420 430 440 450
TEFAKIIAAP ILHVNGDDIE AVLKATNIAV EYRQKFGKDV IVEIICYRKY
460 470 480 490 500
GHNEGDEPMY TQGKMYNIIK SKLTPGNIYA NELVKSGVID NNYFAKLKEQ
510 520 530 540 550
FKAKLDKEYE QAKNYKQEAH FLGGLWQGIT RTRTQVAVTG VDKKTLQSLG
560 570 580 590 600
TKLCEMPKDF AVNPKLVKLF DARKAALTAD QPIDWATAEQ LAFASLLTSG
610 620 630 640 650
TNIRLTGQDC GRGTFSHRHS VLHNQVDDTT YIPLNNLSKE QATYEVADSN
660 670 680 690 700
LSEYAVLGFE YGYSLANPKN LVLWEAQFGD FANGAQIIFD QFISSSETKW
710 720 730 740 750
LRMSGLVVLL PHGFEGQGPE HSSARLERFL QLAAEDNMYV TYPTTPASIF
760 770 780 790 800
HLLRRQIIDN VRKPLIVMSP KSLLRHKNVV SKLDELGSNT TFLPVLDEVN
810 820 830 840 850
KLEASNITKV ILCSGKVYYD LFEMRGSNSS IAIIRLEQLY PFEKKVVVEL
860 870 880 890 900
LKKYNKASEF IWCQEEPMNM GAWRYITSHL NNALKEAGIN NEFKYIGREE
910 920
SASPAVGSLQ AHNKQQEKLL KEALGVK
Length:927
Mass (Da):103,600
Last modified:November 13, 2007 - v1
Checksum:iB900721F48FCEABA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000849 Genomic DNA. Translation: ABV78752.1.
RefSeqiWP_012151656.1. NC_009883.1.
YP_001495789.1. NC_009883.1.

Genome annotation databases

EnsemblBacteriaiABV78752; ABV78752; A1I_01830.
GeneIDi5646295.
KEGGirbo:A1I_01830.
PATRICi17878610. VBIRicBel35792_0385.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000849 Genomic DNA. Translation: ABV78752.1.
RefSeqiWP_012151656.1. NC_009883.1.
YP_001495789.1. NC_009883.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi391896.A1I_01830.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV78752; ABV78752; A1I_01830.
GeneIDi5646295.
KEGGirbo:A1I_01830.
PATRICi17878610. VBIRicBel35792_0385.

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiEHSNARP.
OrthoDBiEOG6V1M1F.

Enzyme and pathway databases

BioCyciRBEL391896:GH75-345-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequencing of Rickettsia bellii."
    Madan A., Lee H., Madan A., Yoon J.-G., Ryu G.-Y., Dasch G., Ereemeva M.
    Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: OSU 85-389Imported.

Entry informationi

Entry nameiA8GV81_RICB8
AccessioniPrimary (citable) accession number: A8GV81
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: March 4, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.