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A8GUS4 (A8GUS4_RICB8) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Name:alr EMBL ABV78571.1
Ordered Locus Names:A1I_00855 EMBL ABV78571.1
OrganismRickettsia bellii (strain OSU 85-389) [Complete proteome] [HAMAP] EMBL ABV78571.1
Taxonomic identifier391896 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiabelli group

Protein attributes

Sequence length410 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS001608

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188 HAMAP-Rule MF_01201

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site831Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site3051Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1821Substrate By similarity HAMAP-Rule MF_01201
Binding site3531Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue831N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
A8GUS4 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 91E898D4A3B5E1B6

FASTA41045,476
        10         20         30         40         50         60 
MSLCTLEINL SAIKANYRLL KNICENSVDF LHNVANKEEF AGNTSPRTAA YTLVREDASL 

        70         80         90        100        110        120 
GSTPKLPLGA SYAKNLLVGA AVKANSYGLG AIEISKTLLE ENCRYFFVAS SNEGISLRKA 

       130        140        150        160        170        180 
IGDEVNILIL NGVFEHDALE LIEYNLIPVL NNLNQIKIWQ KFSNLKNQLL PCYLHFNTGI 

       190        200        210        220        230        240 
NRLGLNHNEI EQLINNRDLL KGLNVEYIIS HLSASEDSDN PYNLEQLNKF KAYLEYFPNA 

       250        260        270        280        290        300 
KASLANSGGI FLGKDYHFNL VRPGAALYGL NPLGSNKPNP MQNPVTLKAP IIHLQNLTYG 

       310        320        330        340        350        360 
SRIGYNMTFT TKRDSLIATL PFGYADGFSR NFSNQGTVFI NSRNVPIIGR ISMDLVNIDV 

       370        380        390        400        410 
TDLPPSDIFL GQEVEIIGNN CTPDKIADII GTIGYEILTS LGNRYKRIYT 

« Hide

References

[1]"Complete genome sequencing of Rickettsia bellii."
Madan A., Lee H., Madan A., Yoon J.-G., Ryu G.-Y., Dasch G., Ereemeva M.
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OSU 85-389 EMBL ABV78571.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000849 Genomic DNA. Translation: ABV78571.1.
RefSeqYP_001495608.1. NC_009883.1.

3D structure databases

ProteinModelPortalA8GUS4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING391896.A1I_00855.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV78571; ABV78571; A1I_00855.
GeneID5647236.
KEGGrbo:A1I_00855.
PATRIC17878185. VBIRicBel35792_0176.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031445.
KOK01775.
OMARIGISIY.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycRBEL391896:GH75-161-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
IPR005728. Rickett_RPE.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
TIGR01045. RPE1. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8GUS4_RICB8
AccessionPrimary (citable) accession number: A8GUS4
Entry history
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: July 9, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)