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Protein

UvrABC system protein C

Gene

uvrC

Organism
Rickettsia rickettsii (strain Sheila Smith)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:A1G_04780
OrganismiRickettsia rickettsii (strain Sheila Smith)
Taxonomic identifieri392021 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
Proteomesi
  • UP000006832 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000778281 – 639UvrABC system protein CAdd BLAST639

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA8GST1.
SMRiA8GST1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 97GIY-YIGUniRule annotationAdd BLAST78
Domaini207 – 242UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279961.
KOiK03703.
OMAiLFPIRQC.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

A8GST1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLEITGSEL IKSKLIDAPE RSGVYRMFDV NKQVLYVGKA KNLKKRLTNY
60 70 80 90 100
IKSNLDNKTL RMIANTCFLE YSITNSEVEA LLLEAQLIKK FQPKFNILLK
110 120 130 140 150
DCKSFPFIKL RLEHDFPQLL KYRGKTLSDG KFFGPFASSV DVNTTLTELQ
160 170 180 190 200
KIFKLRSCTD NYFNSRTRPC LQYEIKRCYA PCVGKINKED YRDLVTQVKD
210 220 230 240 250
FLQGRTKELQ ENLSRKMEEL SSQMRFEEAA EIRDRIKALS YVQLKAGVSD
260 270 280 290 300
VVKDADIIAI VEKNGHYCVE VFLYRAGQAC GNIPYFPTST ENSTKEEVLE
310 320 330 340 350
YFLLQFYQKQ HVPAAIIINH EINDKENVIE AIKKINNILQ LNITVPNKGG
360 370 380 390 400
KAKLVQNAEI NALFSLEQYL KKFAKNQEII FEIKELFGLS AIPERIEIYD
410 420 430 440 450
NSHIQGKFAV GVMVVAGKVG FDKKEYRVFN VYAPSLVCHS RESGDPKRLM
460 470 480 490 500
DSCFRGNGIK NCWGDIKGDD YEMLRQVLTR RLTRLRQEPH KLPSLMIIDG
510 520 530 540 550
GKGHLGVVKE VMDKFEMNIP FVCMSKGVDR NAGFEQFHVI GKEVFTLDKN
560 570 580 590 600
LPVMKYLQIL RDEAHNFAIK NHRLGRSRAI KISRLDDIEG VGETRKKALL
610 620 630
HYFGSYKAVC DATIYELAKV NGINKLLAEM IFNVLHRKN
Length:639
Mass (Da):73,408
Last modified:November 13, 2007 - v1
Checksum:i711C4E8B237ECE2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000848 Genomic DNA. Translation: ABV76456.1.
RefSeqiWP_012151028.1. NC_009882.1.

Genome annotation databases

EnsemblBacteriaiABV76456; ABV76456; A1G_04780.
KEGGirri:A1G_04780.

Similar proteinsi

Entry informationi

Entry nameiUVRC_RICRS
AccessioniPrimary (citable) accession number: A8GST1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 13, 2007
Last modified: October 25, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families