A8GN21 (CAPD_RICAH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UDP-glucose 4-epimerase
EC=5.1.3.2

Alternative name(s):
Galactowaldenase
UDP-galactose 4-epimerase

Gene names

Name:	capD
Ordered Locus Names:	A1C_02485

Organism

Rickettsia akari (strain Hartford) [Complete proteome] [HAMAP]

Taxonomic identifier

293614 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group › Rickettsia akari

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Epimerizes UDP-galactose to UDP-glucose By similarity.
Catalytic activity	UDP-alpha-D-glucose = UDP-alpha-D-galactose.
Sequence similarities	Belongs to the polysaccharide synthase family.

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	UDP-glucose 4-epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	UDP-glucose 4-epimerase		PRO_0000314599

Sequences

	Sequence		Length	Mass (Da)
	A8GN21 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: CC8EAEC7FA93B4DC	FASTA	341	38,285
	10 20 30 40 50 60 MFVDKTLMIT GGTGSFGNAV LSRFLKSDII NDIKEIRIFS RDEKKQEDMR IALSNPKLKF 70 80 90 100 110 120 YIGDVRNYKS IDEAMRGVDY VFHAAALKQV PTCEFYPMEA INTNVLGAEN VLSAAINNKV 130 140 150 160 170 180 AKVIVLSTDK AVYPINAMGL SKALMEKLSI AKARMCSQGE TVLCVTRYGN VMASRGSVIP 190 200 210 220 230 240 LFINQIKQGK ELTITEPSMT RFLMSLVDSV DLVLYAFEHG RQGDIFVQKS PASTIEILAK 250 260 270 280 290 300 ALQEIFGSKN KIRFIGTRHG EKHYESLVSS EDMAKADDLG GYYRIPMDGR DLNYAKYFVE 310 320 330 340 GEKKVALLED YTSHNTKRLN LEEVKKLLLT LDYIQEELKN A

References

[1]	"Complete genome sequence of Rickettsia akari." Madan A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Dasch G., Eremeeva M. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hartford.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000847 Genomic DNA. Translation: ABV74796.1.
RefSeq	YP_001493304.1. NC_009881.1.
3D structure databases
ProteinModelPortal	A8GN21.
ModBase	Search...
Protein-protein interaction databases
STRING	293614.A1C_02485.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABV74796; ABV74796; A1C_02485.
GeneID	5645868.
KEGG	rak:A1C_02485.
PATRIC	17875914. VBIRicAka50705_0508.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1086.
HOGENOM	HOG000257079.
OMA	INAMGLS.
ProtClustDB	CLSK870330.
Enzyme and pathway databases
BioCyc	RAKA293614:GI4A-469-MONOMER.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR016040. NAD(P)-bd_dom. IPR003869. Polysac_CapD-like. IPR013692. Polysac_syn_C. [Graphical view]
Pfam	PF08485. Polysacc_syn_2C. 1 hit. PF02719. Polysacc_synt_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPD_RICAH

Accession

Primary (citable) accession number: A8GN21

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 13, 2007
Last modified:	May 29, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program