A8GM49 (GCP_RICAH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	A1C_00705

Organism

Rickettsia akari (strain Hartford) [Complete proteome] [HAMAP]

Taxonomic identifier

293614 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	386 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 386	386	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000024444

Sequences

	Sequence		Length	Mass (Da)
	A8GM49 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: EA68DEE32694C3B5	FASTA	386	42,389
	10 20 30 40 50 60 MIKILGIESS CDDTAVSIIT ENREILSNII ISQNTEHAVF GGVVPEIAAR SHLSNLDKAL 70 80 90 100 110 120 TNVLKESNTK LIEISAIAAT SGPGLIGGVI VGSMFARSLS STLKKPFIAI NHLEGHALTA 130 140 150 160 170 180 RLTDNIPYPY LLLLASGGHC QFVAVLGLGK YKILGSTIDD AVGETFDKVA KMLNLAFPGG 190 200 210 220 230 240 PEIEQKAKLG DPHKYKFPKP IINSGNCNMS FSGLKTAVRT LIMNLQEINY NECNHLESVR 250 260 270 280 290 300 QDEVQEEFAQ RTKVHEHRRK LQNSLVSSFL NDSVINDIAA SFQFTIGEIL SSKVQDAIRA 310 320 330 340 350 360 YEQITNNFDK KNIIIAGGVA ANKYLQEILS NCAKTYGYQL IYPPIHLCTD NAAMIAYAGL 370 380 ERYNNKLFTP LNFCPKARWS LEDISK

References

[1]	"Complete genome sequence of Rickettsia akari." Madan A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Dasch G., Eremeeva M. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hartford.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000847 Genomic DNA. Translation: ABV74474.1.
RefSeq	YP_001492982.1. NC_009881.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A8GM49.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5645476.
GenomeReviews	Gene locus A1C_00705 in contig CP000847_GR.
KEGG	rak:A1C_00705.
NMPDR	fig|293614.3.peg.129.
PATRIC	17875175. VBIRicAka50705_0146.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	KDCNFSY.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	RAKA293614:A1C_00705-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. IPR022437. RPE3. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit. TIGR03775. RPE3. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_RICAH

Accession

Primary (citable) accession number: A8GM49

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program