A8GM08 (DGTL1_RICAH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxyguanosinetriphosphate triphosphohydrolase-like protein

Gene names

Ordered Locus Names:

A1C_00500

Organism

Rickettsia akari (strain Hartford) [Complete proteome] [HAMAP]

Taxonomic identifier

293614 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dGTPase family. Type 2 subfamily.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	GTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	dGTPase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 391	391	Deoxyguanosinetriphosphate triphosphohydrolase-like protein HAMAP MF_01212		PRO_1000066437

Sequences

	Sequence		Length	Mass (Da)
	A8GM08 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 11A7E5A44C91C1AA	FASTA	391	45,273
	10 20 30 40 50 60 MLASYASDPL KSRGRLYKEI PTSYRNEFEC DRDRIINTNA FRRLQYKTQV FINHEGDHYR 70 80 90 100 110 120 NRLTHSLEVS TVARSVANTL NLSSDLAETI ALAHDLGHTP FGHAGERALN ECMKEYSGFS 130 140 150 160 170 180 HNAQSLKILT LLEKRYAAYN GVNLTWEVLE GIIKHNGPIT GEINEYIAEY NKQNDLELST 190 200 210 220 230 240 YASAEAQIAS LADDISYISH DLEDSIGAKI IDFNSLAELK YIDQHVFELK SKFKNISSSC 250 260 270 280 290 300 LIYEVVRKLM HELITDLLWQ TKENLNKEKI INIYEIRHLN YQIVDFTEKT NDRIKETKKF 310 320 330 340 350 360 LHERVYKSNK ITAISLKCTK IVQGLFKVYM DDINLLPVNW KMLIDSDDTY SKARVIADYI 370 380 390 AGMTDRFAIQ EYNQLCSLNF NNILKLNYEY I

References

[1]	"Complete genome sequence of Rickettsia akari." Madan A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Dasch G., Eremeeva M. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Hartford.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000847 Genomic DNA. Translation: ABV74433.1.
RefSeq	YP_001492941.1. NC_009881.1.
3D structure databases
ProteinModelPortal	A8GM08.
ModBase	Search...
Protein-protein interaction databases
STRING	A8GM08.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5644708.
GenomeReviews	Gene locus A1C_00500 in contig CP000847_GR.
KEGG	rak:A1C_00500.
NMPDR	fig|293614.3.peg.88.
PATRIC	17875087. VBIRicAka50705_0103.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0232.
HOGENOM	HBG500914.
OMA	ITRFVED.
ProtClustDB	PRK01286.
Enzyme and pathway databases
BioCyc	RAKA293614:A1C_00500-MONOMER.
Family and domain databases
HAMAP	MF_01212. dGTPase_type2. [Tree]
InterPro	IPR006261. dGTP_triP_hydro. IPR023293. dGTP_triP_hydro_central. IPR023023. dGTP_triP_hydro_type2. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. [Graphical view]
Gene3D	G3DSA:1.10.3410.10. G3DSA:1.10.3410.10. 1 hit. G3DSA:1.10.3210.10. HD. 1 hit.
KO	K01129.
Pfam	PF01966. HD. 1 hit. [Graphical view]
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01353. DGTP_triPase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DGTL1_RICAH

Accession

Primary (citable) accession number: A8GM08

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program