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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei137UniRule annotation1
Active sitei545UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Spro_4783
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia
Proteomesi
  • UP000007074 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000612331 – 878Phosphoenolpyruvate carboxylaseAdd BLAST878

Proteomic databases

PRIDEiA8GL86

Interactioni

Protein-protein interaction databases

STRINGi399741.Spro_4783

Structurei

3D structure databases

ProteinModelPortaliA8GL86
SMRiA8GL86
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238648
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A8GL86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEQYSAMRS NVSMLGKLLG DTIKEALGEH ILDRVETIRK LSKSSRAGNE
60 70 80 90 100
AHRQELLSTL QNLSNDELLP VARAFSQFLN LTNVAEQYHS ISPNGEAASN
110 120 130 140 150
PEALAQLFTR LKDKKLSTKE LQNAVSQLSI ELVLTAHPTE ITRRTLIHKL
160 170 180 190 200
VEVNTCLSQL DHNDLADYER NKIMRRLRQL VAQSWHTDEI RKHRPSPIDE
210 220 230 240 250
AKWGFAVVEN SLWEGVPAFL REFNEQLENS IDYSLPAEAV PVRFTSWMGG
260 270 280 290 300
DRDGNPNVTA EITRHVLLLS RWKACDLFTR DIQVLVSELS MTECTPELRA
310 320 330 340 350
RAGGDEVQEP YREIMKQLRS QLMSSQAYLE GRLKGERVLK PHDLLVNNEQ
360 370 380 390 400
LWEPLFACYQ SLQACGMSII ANGQLLDTLR RVRCFGVPLV RIDVRQESTR
410 420 430 440 450
HTEAIAELTR YLGLGDYESW SEADKQAFLI RELNSKRPLV PLKWEPSADT
460 470 480 490 500
QEVLETCRVI AEAPQGSIAA YVISMARTPS DVLAVHLLLK EAGCPFALPV
510 520 530 540 550
APLFETLDDL NNADDVMTQL LNIDWYRGFI QGKQMVMIGY SDSAKDAGVM
560 570 580 590 600
AASWAQYRAQ DALIKTCEKA GVALTLFHGR GGSIGRGGAP AHAALLSQPP
610 620 630 640 650
GSLKGGLRVT EQGEMIRFKF GLPEVTISSL ALYTGAILEA NLLPPPEPKK
660 670 680 690 700
EWRALMDDLS DTSCKMYRGY VRENPEFVPY FRAATPELEL GKLPLGSRPA
710 720 730 740 750
KRKPNGGVES LRAIPWIFAW TQNRLMLPAW LGAGAGLQEA VKAGKQDQLE
760 770 780 790 800
AMCRDWPFFS TRIAMLEMVF AKADLWLAEY YDQRLVDKSL WPLGQQLRDQ
810 820 830 840 850
LASDIKVVLT IANDAHLMED LPWIAESIAL RNVYTDPLNV LQAELLHRSR
860 870
QQEQPDARVE QALMVTIAGV AAGMRNTG
Length:878
Mass (Da):98,397
Last modified:November 13, 2007 - v1
Checksum:i5C09BFB7A807C316
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA Translation: ABV43876.1
RefSeqiWP_012147457.1, NC_009832.1

Genome annotation databases

EnsemblBacteriaiABV43876; ABV43876; Spro_4783
KEGGispe:Spro_4783

Similar proteinsi

Entry informationi

Entry nameiCAPP_SERP5
AccessioniPrimary (citable) accession number: A8GL86
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: March 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health