Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

HTH-type transcriptional regulator MalT

Gene

malT

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box): 5'-GGA[TG]GA-3'.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi39 – 46ATPUniRule annotation8
DNA bindingi856 – 875H-T-H motifUniRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processCarbohydrate metabolism, Transcription, Transcription regulation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator MalTUniRule annotation
Alternative name(s):
ATP-dependent transcriptional activator MalTUniRule annotation
Gene namesi
Name:malTUniRule annotation
Ordered Locus Names:Spro_4637
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia
Proteomesi
  • UP000007074 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000857781 – 904HTH-type transcriptional regulator MalTAdd BLAST904

Interactioni

Subunit structurei

Monomer in solution but oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.UniRule annotation

Protein-protein interaction databases

STRINGi399741.Spro_4637

Structurei

3D structure databases

ProteinModelPortaliA8GKU0
SMRiA8GKU0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini832 – 897HTH luxR-typeUniRule annotationAdd BLAST66

Phylogenomic databases

eggNOGiENOG41061ZR Bacteria
COG2909 LUCA
HOGENOMiHOG000218261
KOiK03556
OMAiSDWVSNA
OrthoDBiPOG091H0FN0

Family and domain databases

CDDicd06170 LuxR_C_like, 1 hit
Gene3Di1.10.10.10, 1 hit
1.25.40.10, 1 hit
HAMAPiMF_01247 HTH_type_MalT, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR011990 TPR-like_helical_dom_sf
IPR023768 Tscrpt_reg_HTH_MalT
IPR000792 Tscrpt_reg_LuxR_C
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00196 GerE, 1 hit
PRINTSiPR00038 HTHLUXR
SMARTiView protein in SMART
SM00421 HTH_LUXR, 1 hit
SUPFAMiSSF46894 SSF46894, 1 hit
SSF48452 SSF48452, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00622 HTH_LUXR_1, 1 hit
PS50043 HTH_LUXR_2, 1 hit

Sequencei

Sequence statusi: Complete.

A8GKU0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIPSKLSRP VRLQNTVIRD RLLAKLASTA NYRLTLVNCP AGYGKTTLVA
60 70 80 90 100
QWAAGKSDLG WYSLDESDNQ PERFASYLIA ALQLASGGHC VKSEALSQKH
110 120 130 140 150
QYASLSALFA QLFIELSDWH QPLYLVIDDY HLITNDVIHE AMRFFLRHQP
160 170 180 190 200
ENLTLILLSR TLPPLGIANL RVRDQLLEMG TQQLAFTHQE AKQFFDCRLV
210 220 230 240 250
SPMESQDSSR LCDEVEGWAT ALQLIALSAR QSNSSAQQSA KRLAGLNASH
260 270 280 290 300
LSDYLVDEVL DHVDAEARAF LLRCSVLRSM NDALIVRLTG EDNGQQRLEE
310 320 330 340 350
LERQGLFIHR MDDSGEWFCF HPLFATFLRQ RCQWELALEL PGLHRAAAEG
360 370 380 390 400
WLALGYPAEA IHHALAASDV SMLRDILLQH AWSLFHHSEL ALLEECLNAL
410 420 430 440 450
PYERLIQNPK LALLQAWLAQ SQHRYSEVNT LLERAEQAMR DQKIEVDRTL
460 470 480 490 500
EAEFDALRAQ VAINAGKPEE AERLATEALK FLPLSSYYSR IVATSVTGEV
510 520 530 540 550
HHCKGELARA LPMMQQTEQM ARRHQAYHYA LWALLQQSEI LIAQGFLQAA
560 570 580 590 600
FETQDKAFEL VREQHLEQLP MHEFLLRIRS QILWSWSRLD EAEDAAREGL
610 620 630 640 650
KILANYQPQQ QLQCIAMLAK CSLARGDLDN ANAHMQRCEV LLHGTQYHRD
660 670 680 690 700
WLTNADKPRV IHWQMTGDTT AAAQWLRQTE KPGMADNHFM QGQWRNIARV
710 720 730 740 750
QIMLGQYEEA EVVLDELNEN ARRLRLVSDL NRNLLLSNQL YWQMERKSDA
760 770 780 790 800
QKVLMEALSL ASRTGFISHF VIEGEAMAQQ LRQLIQLNTL PELENHRAQR
810 820 830 840 850
ILRDINQHHR HKFAHFDENF VDKLLTHPQV PELIRTSPLT QREWQVLGLI
860 870 880 890 900
YSGYSNDQIA GELAVAATTI KTHIRNLYQK LGVAHRQEAV QQAQQLLKMM

GYGA
Length:904
Mass (Da):103,392
Last modified:November 13, 2007 - v1
Checksum:i1E0AC421AE3BB3EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA Translation: ABV43730.1
RefSeqiWP_012147312.1, NC_009832.1

Genome annotation databases

EnsemblBacteriaiABV43730; ABV43730; Spro_4637
KEGGispe:Spro_4637

Similar proteinsi

Entry informationi

Entry nameiMALT_SERP5
AccessioniPrimary (citable) accession number: A8GKU0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 13, 2007
Last modified: March 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health