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A8GKD1

- G6PI_SERP5

UniProt

A8GKD1 - G6PI_SERP5

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (13 Nov 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei355 – 3551Proton donorUniRule annotation
    Active sitei386 – 3861UniRule annotation
    Active sitei514 – 5141UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciSPRO399741:GI55-4564-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:Spro_4477
    OrganismiSerratia proteamaculans (strain 568)
    Taxonomic identifieri399741 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia
    ProteomesiUP000007074: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 548548Glucose-6-phosphate isomerasePRO_1000060399Add
    BLAST

    Proteomic databases

    PRIDEiA8GKD1.

    Interactioni

    Protein-protein interaction databases

    STRINGi399741.Spro_4477.

    Structurei

    3D structure databases

    ProteinModelPortaliA8GKD1.
    SMRiA8GKD1. Positions 7-548.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OMAiNCHFVAN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8GKD1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKNINPSQTA AWQALQQHFE QMKDVQISDL FAQDKERFSK FSATFNDQML    50
    VDYSKNRISA ETLEKLQALA KETDLQSAIK SMFAGEKINR TEDRAVLHVA 100
    LRNRSNTPII VDGKDVMPEV NAVLAKMKQF CDRVIGGDWK GYTGKAITDV 150
    VNIGIGGSDL GPYMATEALR PYKNHLNMHF VSNVDGTHIA ETLQPLNPET 200
    TLFLVASKTF TTQETMTNAH SARDWFLSTA GDQKHVAKHF AALSTNGKAV 250
    GGFGIDTANM FEFWDWVGGR YSLWSAIGLS IALSLGFDNF EQLLSGAHAM 300
    DQHFAQTPAE KNLPVLLALI GIWYNNFFGA ETEAILPYDQ YMHRFAAYFQ 350
    QGNMESNGKY VDRNGNPVDY QTGPIIWGEP GTNGQHAFYQ LIHQGTKLVP 400
    CDFIAPAISH NPLSDHHAKL LSNFFAQTEA LAFGKSLEVV EAEFAAQGKT 450
    PEEVKHVAPF KVFEGNRPTN SILLREITPF SLGSLIALYE HKIFTQGAIL 500
    NIFTFDQWGV ELGKQLANRI LPELAGDEAV SSHDSSTNAL INRFKEWR 548
    Length:548
    Mass (Da):61,018
    Last modified:November 13, 2007 - v1
    Checksum:i3F8950438FF64D2E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000826 Genomic DNA. Translation: ABV43571.1.
    RefSeqiYP_001480699.1. NC_009832.1.

    Genome annotation databases

    EnsemblBacteriaiABV43571; ABV43571; Spro_4477.
    GeneIDi5602562.
    KEGGispe:Spro_4477.
    PATRICi32421770. VBISerPro44537_4531.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000826 Genomic DNA. Translation: ABV43571.1 .
    RefSeqi YP_001480699.1. NC_009832.1.

    3D structure databases

    ProteinModelPortali A8GKD1.
    SMRi A8GKD1. Positions 7-548.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 399741.Spro_4477.

    Proteomic databases

    PRIDEi A8GKD1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABV43571 ; ABV43571 ; Spro_4477 .
    GeneIDi 5602562.
    KEGGi spe:Spro_4477.
    PATRICi 32421770. VBISerPro44537_4531.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OMAi NCHFVAN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci SPRO399741:GI55-4564-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 568.

    Entry informationi

    Entry nameiG6PI_SERP5
    AccessioniPrimary (citable) accession number: A8GKD1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: November 13, 2007
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3