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Protein

Uronate isomerase

Gene

uxaC

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:Spro_4321
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia
Proteomesi
  • UP000007074 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000619521 – 470Uronate isomeraseAdd BLAST470

Proteomic databases

PRIDEiA8GJX5.

Interactioni

Protein-protein interaction databases

STRINGi399741.Spro_4321.

Structurei

3D structure databases

ProteinModelPortaliA8GJX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

A8GJX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATFLSEDFL LGNEFARRLY HDYAADQPIF DYHCHLPPEQ IAENTRFKNL
60 70 80 90 100
YEIWLKGDHY KWRAMRTNGV AERLCTGDAG DREKFDAWAA TVPHTIGNPL
110 120 130 140 150
YHWTHLELRR PFGITGTLLS PTTADDIWQR GNALLAQDDF RARGIMQQMN
160 170 180 190 200
VKMVGTTDDP IDDLRHHKAI AADSSFDIKV LPSWRPDKAF NIDAPGFNDY
210 220 230 240 250
LQKLEAAADI NIGRFSALCD ALKKRMDHFA AHGCKVADHA LDVVVYGEAD
260 270 280 290 300
ESTLDAILTA RLSGKLPTPE QSAQFKSAVL LFLAAEYQRR EWVQQYHIGA
310 320 330 340 350
LRNNNSRMLA SVGPDIGFDS INDRPLAEAL SRLLDAQARQ GGLPKTILYC
360 370 380 390 400
LNPRDNEVIG TMVGNFQGEG TPGKMQFGSG WWFNDQKDGM QRQMTQLAQL
410 420 430 440 450
GLLSRFVGML TDSRSFLSYT RHEYFRRILC QMIGGWVENG EAPADITLLG
460 470
EMVKNICFDN AKNYFAIELA
Length:470
Mass (Da):53,062
Last modified:November 13, 2007 - v1
Checksum:iF77E7E51C7D9B43C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA. Translation: ABV43415.1.
RefSeqiWP_012147018.1. NC_009832.1.

Genome annotation databases

EnsemblBacteriaiABV43415; ABV43415; Spro_4321.
KEGGispe:Spro_4321.
PATRICi32421458. VBISerPro44537_4375.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA. Translation: ABV43415.1.
RefSeqiWP_012147018.1. NC_009832.1.

3D structure databases

ProteinModelPortaliA8GJX5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi399741.Spro_4321.

Proteomic databases

PRIDEiA8GJX5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV43415; ABV43415; Spro_4321.
KEGGispe:Spro_4321.
PATRICi32421458. VBISerPro44537_4375.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_SERP5
AccessioniPrimary (citable) accession number: A8GJX5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: November 2, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.