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Protein

Ribosomal RNA large subunit methyltransferase G

Gene

rlmG

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(1835) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciSPRO399741:GI55-4398-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase GUniRule annotation (EC:2.1.1.174UniRule annotation)
Alternative name(s):
23S rRNA m2G1835 methyltransferaseUniRule annotation
rRNA (guanine-N(2)-)-methyltransferase RlmGUniRule annotation
Gene namesi
Name:rlmGUniRule annotation
Ordered Locus Names:Spro_4312
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia
Proteomesi
  • UP000007074 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 379379Ribosomal RNA large subunit methyltransferase GPRO_0000366503Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi399741.Spro_4312.

Structurei

3D structure databases

ProteinModelPortaliA8GJW6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D8J. Bacteria.
COG2813. LUCA.
HOGENOMiHOG000246323.
KOiK00564.
OMAiFHQQQVV.
OrthoDBiPOG091H05RK.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01859. 23SrRNA_methyltr_G. 1 hit.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
[Graphical view]
PIRSFiPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

A8GJW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQLDLGTQQ LELERYPQQE ESTQLQAWEA ADEYLLQQLE NVNIGDRPVL
60 70 80 90 100
IFNDNFGTLA CALHSHQPYS ISDSYMSQLA TRHNLKLNEL DPQQVTLLDT
110 120 130 140 150
LAELPASPAV VLIRIPKALA LLEQQLRALR DVVAPDTVII AGAKARDVHT
160 170 180 190 200
STMQLFEKVL GPTRTSLAWK KARLIHCEVA DIVPPAAPVT TNWVLDGTDW
210 220 230 240 250
VIHNHANVFS RSNLDIGARL FLDHLPHDIE GHIIDLGCGN GVIGMAALMQ
260 270 280 290 300
NPQAQVSFVD ESYMAVASSE LNVEHNLPQD MDRCQFEVNN SLAGIERESV
310 320 330 340 350
QAVLCNPPFH QQHAITDHTA WQMFCDAKRC LQVGGELRIV GNRHLDYHQK
360 370
LKRLFGNCTL IASNKKFVIL KAVKSGARY
Length:379
Mass (Da):42,282
Last modified:November 13, 2007 - v1
Checksum:iEDE09A80FEDFFB6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA. Translation: ABV43406.1.
RefSeqiWP_012147009.1. NC_009832.1.

Genome annotation databases

EnsemblBacteriaiABV43406; ABV43406; Spro_4312.
KEGGispe:Spro_4312.
PATRICi32421440. VBISerPro44537_4366.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA. Translation: ABV43406.1.
RefSeqiWP_012147009.1. NC_009832.1.

3D structure databases

ProteinModelPortaliA8GJW6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi399741.Spro_4312.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV43406; ABV43406; Spro_4312.
KEGGispe:Spro_4312.
PATRICi32421440. VBISerPro44537_4366.

Phylogenomic databases

eggNOGiENOG4105D8J. Bacteria.
COG2813. LUCA.
HOGENOMiHOG000246323.
KOiK00564.
OMAiFHQQQVV.
OrthoDBiPOG091H05RK.

Enzyme and pathway databases

BioCyciSPRO399741:GI55-4398-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01859. 23SrRNA_methyltr_G. 1 hit.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR017237. rRNA_m2G-MeTrfase_RsmD.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
[Graphical view]
PfamiPF05175. MTS. 1 hit.
[Graphical view]
PIRSFiPIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRLMG_SERP5
AccessioniPrimary (citable) accession number: A8GJW6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: November 13, 2007
Last modified: September 7, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.