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A8GJ45

- GLSA_SERP5

UniProt

A8GJ45 - GLSA_SERP5

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Protein

Glutaminase

Gene
glsA, Spro_4040
Organism
Serratia proteamaculans (strain 568)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei66 – 661Substrate By similarity
Binding sitei117 – 1171Substrate By similarity
Binding sitei161 – 1611Substrate By similarity
Binding sitei168 – 1681Substrate By similarity
Binding sitei192 – 1921Substrate By similarity
Binding sitei243 – 2431Substrate By similarity
Binding sitei261 – 2611Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciSPRO399741:GI55-4124-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:Spro_4040
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia
ProteomesiUP000007074: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307GlutaminaseUniRule annotationPRO_1000059441Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi399741.Spro_4040.

Structurei

3D structure databases

ProteinModelPortaliA8GJ45.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A8GJ45-1 [UniParc]FASTAAdd to Basket

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MVTTLDNALL EEILQQVRPL IGQGKVADYI PALAEVASDR LAIAVCTVDG    50
EIFQAGNATE RFSIQSISKV LSLTLALTRY QEHEIWQRVG KEPSGLPFNS 100
LLQLEMEQGK PRNPFINPGA LVVCDMLQTR LSAPKQRMLE VVRQLAGEED 150
LAYDSRVARS EFEHSDRNAA IAYLMKSFGN FENDVLTVLQ TYFHYCALRM 200
SCLELARSFV YLANHGRDLS GREVISPLQA RQINALMMTS GMYDGAGEFA 250
YRVGMPGKSG VGGGIVAIVP DELSIAVWSP ELDASGNSLA GTAALELLSQ 300
RISRSIF 307
Length:307
Mass (Da):33,676
Last modified:November 13, 2007 - v1
Checksum:i9504DDE6D07AD019
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000826 Genomic DNA. Translation: ABV43135.1.
RefSeqiWP_012146742.1. NC_009832.1.
YP_001480263.1. NC_009832.1.

Genome annotation databases

EnsemblBacteriaiABV43135; ABV43135; Spro_4040.
GeneIDi5605792.
KEGGispe:Spro_4040.
PATRICi32420903. VBISerPro44537_4099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000826 Genomic DNA. Translation: ABV43135.1 .
RefSeqi WP_012146742.1. NC_009832.1.
YP_001480263.1. NC_009832.1.

3D structure databases

ProteinModelPortali A8GJ45.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 399741.Spro_4040.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABV43135 ; ABV43135 ; Spro_4040 .
GeneIDi 5605792.
KEGGi spe:Spro_4040.
PATRICi 32420903. VBISerPro44537_4099.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci SPRO399741:GI55-4124-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 568.

Entry informationi

Entry nameiGLSA_SERP5
AccessioniPrimary (citable) accession number: A8GJ45
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: September 3, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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