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A8GJ45 (GLSA_SERP5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:Spro_4040
OrganismSerratia proteamaculans (strain 568) [Complete proteome] [HAMAP]
Taxonomic identifier399741 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Glutaminase HAMAP-Rule MF_00313
PRO_1000059441

Sites

Binding site661Substrate By similarity
Binding site1171Substrate By similarity
Binding site1611Substrate By similarity
Binding site1681Substrate By similarity
Binding site1921Substrate By similarity
Binding site2431Substrate By similarity
Binding site2611Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A8GJ45 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 9504DDE6D07AD019

FASTA30733,676
        10         20         30         40         50         60 
MVTTLDNALL EEILQQVRPL IGQGKVADYI PALAEVASDR LAIAVCTVDG EIFQAGNATE 

        70         80         90        100        110        120 
RFSIQSISKV LSLTLALTRY QEHEIWQRVG KEPSGLPFNS LLQLEMEQGK PRNPFINPGA 

       130        140        150        160        170        180 
LVVCDMLQTR LSAPKQRMLE VVRQLAGEED LAYDSRVARS EFEHSDRNAA IAYLMKSFGN 

       190        200        210        220        230        240 
FENDVLTVLQ TYFHYCALRM SCLELARSFV YLANHGRDLS GREVISPLQA RQINALMMTS 

       250        260        270        280        290        300 
GMYDGAGEFA YRVGMPGKSG VGGGIVAIVP DELSIAVWSP ELDASGNSLA GTAALELLSQ 


RISRSIF 

« Hide

References

[1]"Complete sequence of chromosome of Serratia proteamaculans 568."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. expand/collapse author list , Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P.
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 568.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000826 Genomic DNA. Translation: ABV43135.1.
RefSeqYP_001480263.1. NC_009832.1.

3D structure databases

ProteinModelPortalA8GJ45.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING399741.Spro_4040.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV43135; ABV43135; Spro_4040.
GeneID5605792.
KEGGspe:Spro_4040.
PATRIC32420903. VBISerPro44537_4099.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAVNSIMAT.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycSPRO399741:GI55-4124-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_SERP5
AccessionPrimary (citable) accession number: A8GJ45
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: February 19, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families