A8GIE8 (GLND_SERP5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	Spro_3792

Organism

Serratia proteamaculans (strain 568) [Complete proteome] [HAMAP]

Taxonomic identifier

399741 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Serratia › Serratia proteamaculans

Protein attributes

Sequence length	892 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: HAMAP
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 892	892	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_1000059226

Sequences

	Sequence		Length	Mass (Da)
	A8GIE8 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 8D6DC4E817EDB145	FASTA	892	103,200
	10 20 30 40 50 60 MSENFRQQDT SVISPQAVPV QPEYPNAYGD EEINCIALKQ RLEQFQLWLA AAFNAGSSAE 70 80 90 100 110 120 SLVAARSDFI DRLLRRLWVF YGFEDIPETA LVAVGGYGRG ELHPLSDIDV LVLSQRRLNE 130 140 150 160 170 180 QQSQRVGEFI TLLWDLKLEV GHSVRTLEEC LLEGLADLTV ATNLIESRMI CGDVALFLQM 190 200 210 220 230 240 QKHIFSDGFW PSPQFFHAKV VEQQERHQRY HGTSYNLEPD IKSSPGGLRD IHTLLWVARR 250 260 270 280 290 300 HFGATSLDEM VGFGFLTQAE RNELNECQSF LWRIRFALHL VLPRYDNRLL FDRQLNVAQL 310 320 330 340 350 360 LRYEGEGNEP VERMMKDFYR MTRRVGELNH MLLQLFDEAI LALDATEKPR PLNDDFQLRG 370 380 390 400 410 420 DLIDLRDETL FIRQPESIMR MFYLMVRNRE IKGIYSTTVR QLRHARRHLK QPLCTIPEAR 430 440 450 460 470 480 ELFMAILRHP GAVSRALVPM HRHSVLWAYM PQWGKIVGQM QFDLFHAYTV DEHTIRVLQK 490 500 510 520 530 540 LESFADAETR PRHPLCVELY PRLPNPELLL LAALFHDIAK GRGGDHSILG AQDVLEFAEV 550 560 570 580 590 600 HGLNSREAQL VAWLVRCHLL MSVTAQRRDI QDPTVIQQFS AEVQSETRLR YLVCLTVADI 610 620 630 640 650 660 CATNETLWNS WKQSLLRELY FATEKQLRRG MQNSPDLRER VRHHRLQALA LLRMDNIDEE 670 680 690 700 710 720 ALHRIWSRCR ADYFLRHSPN QLAWHARHLL AHDSTKPLVL VSRQATRGGT EIFIWSPDRP 730 740 750 760 770 780 YLFAAVAGEM DRRNLSVHDA QIFTNRDGMA MDTFIVLEPD GSPLAQDRHT AIRHALLQAI 790 800 810 820 830 840 TQREYQPPRV RRPSSKLRHF SVPTEVSFLP THTDRRSYLE LTALDQPGLL ARVGEVFADL 850 860 870 880 890 NLSLHGARIS TIGERVEDLF ILADSDRRAL NPETRRKLEQ RLTEALNPND KM

References

[1]

"Complete sequence of chromosome of Serratia proteamaculans 568." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. , Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 568.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000826 Genomic DNA. Translation: ABV42888.1.
RefSeq	YP_001480016.1. NC_009832.1.
3D structure databases
ProteinModelPortal	A8GIE8.
ModBase	Search...
Protein-protein interaction databases
STRING	399741.Spro_3792.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABV42888; ABV42888; Spro_3792.
GeneID	5607191.
KEGG	spe:Spro_3792.
PATRIC	32420400. VBISerPro44537_3852.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261778.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK05007.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_SERP5

Accession

Primary (citable) accession number: A8GIE8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	May 1, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program