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Protein

D-cysteine desulfhydrase

Gene

dcyD

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.UniRule annotation

Catalytic activityi

D-cysteine + H2O = H2S + NH3 + pyruvate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionLyase
LigandPyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
D-cysteine desulfhydraseUniRule annotation (EC:4.4.1.15UniRule annotation)
Gene namesi
Name:dcyDUniRule annotation
Ordered Locus Names:Spro_2937
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia
Proteomesi
  • UP000007074 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000642661 – 330D-cysteine desulfhydraseAdd BLAST330

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei52N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi399741.Spro_2937

Structurei

3D structure databases

ProteinModelPortaliA8GFZ8
SMRiA8GFZ8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ACC deaminase/D-cysteine desulfhydrase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105K6H Bacteria
COG2515 LUCA
HOGENOMiHOG000022459
KOiK05396
OMAiAKIGMKC
OrthoDBiPOG091H0B2C

Family and domain databases

HAMAPiMF_01045 D_Cys_desulfhydr, 1 hit
InterProiView protein in InterPro
IPR027278 ACCD_DCysDesulf
IPR005966 D-Cys_desShydrase
IPR023702 D_Cys_desulphydr_bac
IPR001926 PLP-dep
IPR036052 Trypto_synt_PLP_dependent
PfamiView protein in Pfam
PF00291 PALP, 1 hit
PIRSFiPIRSF006278 ACCD_DCysDesulf, 1 hit
SUPFAMiSSF53686 SSF53686, 1 hit
TIGRFAMsiTIGR01275 ACC_deam_rel, 1 hit

Sequencei

Sequence statusi: Complete.

A8GFZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLQQKLAQF PRLDLVGSAT PLEKLSRLSD YLGREIYIKR DDVTPMAMGG
60 70 80 90 100
NKLRKLEFLA ADALRQGADT LVTAGAIQSN HVRQTAAVAA KLGLHCVALL
110 120 130 140 150
ENPIDTQEEN YLTNGNRLLL GLFNAQVEMC EALHDPQQQL ADLATRLEAQ
160 170 180 190 200
GFRPYVVPVG GSNALGALGY VQCALEIAEQ SQRSNVAFSS VVVASGSAGT
210 220 230 240 250
HAGLAVGLQQ LLPETELVGV TVSRKVIDQL PKVEQIQKAL ANSLAIDELA
260 270 280 290 300
PITLWDDYFA PQYGMPNEEG LAAIQLLAQQ EGVLLDPVYS GKAMAGLIDG
310 320 330
VAQQRFRDDG PILFIHTGGA PALFAYHPQV
Length:330
Mass (Da):35,433
Last modified:November 13, 2007 - v1
Checksum:i1BABE72DF0178047
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA Translation: ABV42038.1
RefSeqiWP_012145659.1, NC_009832.1

Genome annotation databases

EnsemblBacteriaiABV42038; ABV42038; Spro_2937
KEGGispe:Spro_2937

Similar proteinsi

Entry informationi

Entry nameiDCYD_SERP5
AccessioniPrimary (citable) accession number: A8GFZ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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