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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Spro_2791
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia
Proteomesi
  • UP000007074 Componenti: Chromosome

Subcellular locationi

A8GFK2:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000578121 – 576Arginine--tRNA ligaseAdd BLAST576

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi399741.Spro_2791.

Structurei

3D structure databases

ProteinModelPortaliA8GFK2.
SMRiA8GFK2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

A8GFK2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQVLLSDK VSQALIAAGA PADCEAQVRQ SAKAQFGDYQ ANGVMSVAKK
60 70 80 90 100
LGMPPRQLAE KVVQLLDLGD VASKVEIAGP GFINIFLNSQ WVAQQADRVL
110 120 130 140 150
SAPKLDIAPV KQQTIVIDYS APNVAKEMHV GHLRSTIIGD AAARTQEFLG
160 170 180 190 200
HKVIRANHVG DWGTQFGMLI AYLEKMQNEN ASDMGLSDLE QFYREAKKHY
210 220 230 240 250
DEDADFAERA RAYVVKLQGG DQYCLKMWRK LVDITMAQNQ LTYNRLNVTL
260 270 280 290 300
TEDDVMGESL YNAMLPGIVA DLKAKGLAVE SEGATVVFLD EYKNKDGEPM
310 320 330 340 350
GVIIQKKDGG YLYTTTDIAC AKYRYETLGA DRVLYYIDSR QHQHLMQAWT
360 370 380 390 400
IVRKAGYIPD SLSLEHHMFG MMLGKDGKPF KTRSGGTVKL SDLLDEAVDR
410 420 430 440 450
AGKLIAEKNP DMPAEEMQSL ANAVGIGAVK YADLSKSRTT DYIFDWDNML
460 470 480 490 500
AFEGNTAPYM QYAYTRVASV FKRAGVDESN LTLPLVMTEE REITLATRLL
510 520 530 540 550
QFEEVITTVA REGTPHVMCS YLYDLAGLFS GFYEHCQILN ADSEEARQSR
560 570
LKLSLLTAKT LKVGLDTLGI ETVERM
Length:576
Mass (Da):63,989
Last modified:November 13, 2007 - v1
Checksum:i37473D9EFDDEDA18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA. Translation: ABV41892.1.
RefSeqiWP_012145515.1. NC_009832.1.

Genome annotation databases

EnsemblBacteriaiABV41892; ABV41892; Spro_2791.
KEGGispe:Spro_2791.

Similar proteinsi

Entry informationi

Entry nameiSYR_SERP5
AccessioniPrimary (citable) accession number: A8GFK2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: October 25, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families