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A8GCJ6 (PNCB_SERP5) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:Spro_1732
OrganismSerratia proteamaculans (strain 568) [Complete proteome] [HAMAP]
Taxonomic identifier399741 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000061169

Sequences

Sequence LengthMass (Da)Tools
A8GCJ6 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 84A2D01CD36318F5

FASTA40145,452
        10         20         30         40         50         60 
MTQYASPILT SLLDTDAYKL HMQQAVFHRY PAISVAAEFR CRGDELLGEY ADEIGAQIAL 

        70         80         90        100        110        120 
MSQLALTDAE FDYLSGLPFF REDYLNWLRD FRYDPQQVQI ENHAGKLHIR IAGPWREVIM 

       130        140        150        160        170        180 
WEVPLLAVIS EVVHRHRSPD VTPEMAVAHL RNKLAQFKAM SSDVDISRFK LMDFGTRRRF 

       190        200        210        220        230        240 
SQAVQQAIVG TLKNEFPYLV GTSNYDLAHQ LDLAPVGTQA HEWFQAHQQI SPVLANSQRA 

       250        260        270        280        290        300 
ALQAWLDEYP DQLGIALTDC ITMDAFLRDF GPQFAQRYQG LRHDSGDPFE WGEKAIAHFQ 

       310        320        330        340        350        360 
KLGIDPMSKT LVFSDNLDLD KALALYRHFY QRVNLVFGIG TRLTCDIPGV KPLNIVIKLV 

       370        380        390        400 
ECKGKPVAKL SDSPGKTICQ DQAFVKALRK AFDLPLVKKA S 

« Hide

References

[1]"Complete sequence of chromosome of Serratia proteamaculans 568."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. expand/collapse author list , Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P.
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 568.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000826 Genomic DNA. Translation: ABV40836.1.
RefSeqYP_001477964.1. NC_009832.1.

3D structure databases

ProteinModelPortalA8GCJ6.
SMRA8GCJ6. Positions 3-377.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING399741.Spro_1732.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV40836; ABV40836; Spro_1732.
GeneID5604586.
KEGGspe:Spro_1732.
PATRIC32416157. VBISerPro44537_1763.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycSPRO399741:GI55-1782-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_SERP5
AccessionPrimary (citable) accession number: A8GCJ6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: March 19, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways