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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:Spro_1676
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeSerratia
Proteomesi
  • UP000007074 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000620091 – 241Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST241

Interactioni

Protein-protein interaction databases

STRINGi399741.Spro_1676

Structurei

3D structure databases

ProteinModelPortaliA8GCE0
SMRiA8GCE0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

A8GCE0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIVKLSPHS LAFPSPEGAL RDPNGLLAIG GDLTAPRLLA AYERGIFPWF
60 70 80 90 100
SPGEAILWWS PDPRAVLFPA ERHISRSLKR FLRSNPFRVT LNHDFAAVIA
110 120 130 140 150
ACADRPEEGT WIGPEVQRAY LHLHRLGFAH SIEVWQGDEL VGGMYGVAQG
160 170 180 190 200
ALFCGESMFS RTTNASKCAL MTFCRHFAAY GGELIDCQVL NAHTATLGAK
210 220 230 240
EIPRRQFLQQ LSQLQRKPLA PECWAPQVLP PQQVEPPSPT N
Length:241
Mass (Da):26,719
Last modified:November 13, 2007 - v1
Checksum:i1E8BB1D7CF7C91E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA Translation: ABV40780.1
RefSeqiWP_012006107.1, NC_009832.1

Genome annotation databases

EnsemblBacteriaiABV40780; ABV40780; Spro_1676
KEGGispe:Spro_1676

Similar proteinsi

Entry informationi

Entry nameiLFTR_SERP5
AccessioniPrimary (citable) accession number: A8GCE0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: March 28, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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