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Protein

Deoxyribose-phosphate aldolase

Gene

deoC

Organism
Serratia proteamaculans (strain 568)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.UniRule annotationSAAS annotation

Catalytic activityi

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei156 – 1561Schiff-base intermediate with acetaldehydeUniRule annotation
Active sitei185 – 1851UniRule annotation

GO - Molecular functioni

  1. deoxyribose-phosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate catabolic process Source: UniProtKB-HAMAP
  2. deoxyribonucleotide catabolic process Source: InterPro
  3. deoxyribose phosphate catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Ligandi

Schiff baseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSPRO399741:GI55-1682-MONOMER.
UniPathwayiUPA00002; UER00468.
UPA00002; UER00468.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxyribose-phosphate aldolaseUniRule annotationSAAS annotation (EC:4.1.2.4UniRule annotationSAAS annotation)
Short name:
DERAUniRule annotation
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolaseUniRule annotation
PhosphodeoxyriboaldolaseUniRule annotation
Gene namesi
Name:deoCUniRule annotation
Ordered Locus Names:Spro_1632Imported
OrganismiSerratia proteamaculans (strain 568)Imported
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia
ProteomesiUP000007074: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi399741.Spro_1632.

Structurei

3D structure databases

ProteinModelPortaliA8GC96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0274.
HOGENOMiHOG000241645.
KOiK01619.
OMAiEICMDAG.
OrthoDBiEOG6QZMW5.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00114. DeoC_type1.
InterProiIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR028581. DeoC_typeI.
[Graphical view]
PANTHERiPTHR10889. PTHR10889. 1 hit.
PfamiPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFiPIRSF001357. DeoC. 1 hit.
TIGRFAMsiTIGR00126. deoC. 1 hit.

Sequencei

Sequence statusi: Complete.

A8GC96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTENIDYAR YVDHTLLAMD ATEEQIAKLC EEAQQHNFYA VCVNSGYVPL
60 70 80 90 100
AAHLLQESEV KICSVIGFPL GAGLTVTKAF EAKAAIAAGA QEIDMVINVG
110 120 130 140 150
WLKSGLLDEV KADIAAVREV CAAIPLKVIL ETCLLSDAQI VQVCEMCREL
160 170 180 190 200
DVAFVKTSTG FSTGGAREEH VKLMRATVGS EMGVKASGAV RDRATAEKMI
210 220
KAGATRIGTS SGVAIVSGDQ AAAGSY
Length:226
Mass (Da):23,830
Last modified:November 13, 2007 - v1
Checksum:i6DE727D9910FDE0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA. Translation: ABV40736.1.
RefSeqiYP_001477864.1. NC_009832.1.

Genome annotation databases

EnsemblBacteriaiABV40736; ABV40736; Spro_1632.
GeneIDi5603995.
KEGGispe:Spro_1632.
PATRICi32415954. VBISerPro44537_1662.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA. Translation: ABV40736.1.
RefSeqiYP_001477864.1. NC_009832.1.

3D structure databases

ProteinModelPortaliA8GC96.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi399741.Spro_1632.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV40736; ABV40736; Spro_1632.
GeneIDi5603995.
KEGGispe:Spro_1632.
PATRICi32415954. VBISerPro44537_1662.

Phylogenomic databases

eggNOGiCOG0274.
HOGENOMiHOG000241645.
KOiK01619.
OMAiEICMDAG.
OrthoDBiEOG6QZMW5.

Enzyme and pathway databases

UniPathwayiUPA00002; UER00468.
UPA00002; UER00468.
BioCyciSPRO399741:GI55-1682-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00114. DeoC_type1.
InterProiIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR028581. DeoC_typeI.
[Graphical view]
PANTHERiPTHR10889. PTHR10889. 1 hit.
PfamiPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFiPIRSF001357. DeoC. 1 hit.
TIGRFAMsiTIGR00126. deoC. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 568Imported.

Entry informationi

Entry nameiA8GC96_SERP5
AccessioniPrimary (citable) accession number: A8GC96
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: March 4, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.