Reviewed, UniProtKB/Swiss-Prot A8GBC1 (6PGL_SERP5)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6-P-gluconolactonase
    EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	Spro_1307

Organism

Serratia proteamaculans (strain 568) [Complete proteome] [HAMAP]

Taxonomic identifier

399741 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Serratia

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	6-phosphogluconolactonase HAMAP MF_01605		PRO_1000069412

Sequences

	Sequence		Length	Mass (Da)
	A8GBC1-1 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 551F984B69D94F66	FASTA	331	35,802
	10 20 30 40 50 60 MKQIVYVASP ESQQIHVWQL SDAGALELLQ TVEAPGQVQP MAIHPDRTHL YVGVRPAFGI 70 80 90 100 110 120 VSYRIEADGT LQQAGMAPLP GSPTHISTDL QGRYLFSASY SGNCASVSPI GHDGVVVAPI 130 140 150 160 170 180 QQIDGLTAPH SANIDPTNQL LLVPCLKEDR IRLFNLDLQG ELTPHTQEAV TTASGAGPRH 190 200 210 220 230 240 MAFHHNDKYA YCVNELDGTV DVFAISENGG KYTLVQTLDI MPADFNGTRW AADIHITPNG 250 260 270 280 290 300 RFLYTSDRTA SILTIFSVSE DGSTLSVVGY HPTEEQPRGF NIDHSGRFVI SSGQKSGHIG 310 320 330 VYEIDQASGK LTTLARYPVG KGPMWVSILA K

References

[1]

"Complete sequence of chromosome of Serratia proteamaculans 568." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. , Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000826 Genomic DNA. Translation: ABV40411.1.
RefSeq	YP_001477539.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A8GBC1.
Genome annotation databases
GeneID	5605237.
GenomeReviews	Gene locus Spro_1307 in contig CP000826_GR.
KEGG	spe:Spro_1307.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EGCHSAN.
Family and domain databases
HAMAP	MF_01605. [Tree]
InterPro	IPR019405. DUF2394. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF10282. DUF2394. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

6PGL_SERP5

Accession

Primary (citable) accession number: A8GBC1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	November 3, 2009
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)