A8GBC1 (6PGL_SERP5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
6-phosphogluconolactonase
Short name=6-P-gluconolactonase
EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	Spro_1307

Organism

Serratia proteamaculans (strain 568) [Complete proteome] [HAMAP]

Taxonomic identifier

399741 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Serratia

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	6-phosphogluconolactonase HAMAP MF_01605		PRO_1000069412

Sequences

	Sequence		Length	Mass (Da)
	A8GBC1 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 551F984B69D94F66	FASTA	331	35,802
	10 20 30 40 50 60 MKQIVYVASP ESQQIHVWQL SDAGALELLQ TVEAPGQVQP MAIHPDRTHL YVGVRPAFGI 70 80 90 100 110 120 VSYRIEADGT LQQAGMAPLP GSPTHISTDL QGRYLFSASY SGNCASVSPI GHDGVVVAPI 130 140 150 160 170 180 QQIDGLTAPH SANIDPTNQL LLVPCLKEDR IRLFNLDLQG ELTPHTQEAV TTASGAGPRH 190 200 210 220 230 240 MAFHHNDKYA YCVNELDGTV DVFAISENGG KYTLVQTLDI MPADFNGTRW AADIHITPNG 250 260 270 280 290 300 RFLYTSDRTA SILTIFSVSE DGSTLSVVGY HPTEEQPRGF NIDHSGRFVI SSGQKSGHIG 310 320 330 VYEIDQASGK LTTLARYPVG KGPMWVSILA K

References

[1]

"Complete sequence of chromosome of Serratia proteamaculans 568." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. , Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 568.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000826 Genomic DNA. Translation: ABV40411.1.
RefSeq	YP_001477539.1. NC_009832.1.
3D structure databases
ProteinModelPortal	A8GBC1.
SMR	A8GBC1. Positions 1-330.
ModBase	Search...
Protein-protein interaction databases
STRING	A8GBC1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5605237.
GenomeReviews	Gene locus Spro_1307 in contig CP000826_GR.
KEGG	spe:Spro_1307.
PATRIC	32415310. VBISerPro44537_1340.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2706.
HOGENOM	HBG741123.
OMA	TLDIMPA.
ProtClustDB	PRK11028.
Enzyme and pathway databases
BioCyc	SPRO399741:SPRO_1307-MONOMER.
Family and domain databases
HAMAP	MF_01605. 6P-gluconolactonase. [Tree]
InterPro	IPR022528. 6-phosphogluconolactonase_YbhE. IPR019405. Lactonase_7-beta_prop. IPR011045. N2O_reductase_N. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
KO	K07404.
Pfam	PF10282. Lactonase. 1 hit. [Graphical view]
SUPFAM	SSF50974. N2O_reductase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_SERP5

Accession

Primary (citable) accession number: A8GBC1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program