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A8GBC1

- 6PGL_SERP5

UniProt

A8GBC1 - 6PGL_SERP5

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Protein
6-phosphogluconolactonase
Gene
pgl, Spro_1307
Organism
Serratia proteamaculans (strain 568)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.UniRule annotation

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

BioCyciSPRO399741:GI55-1357-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6-P-gluconolactonase
Gene namesi
Name:pgl
Ordered Locus Names:Spro_1307
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia
ProteomesiUP000007074: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3313316-phosphogluconolactonaseUniRule annotation
PRO_1000069412Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi399741.Spro_1307.

Structurei

3D structure databases

ProteinModelPortaliA8GBC1.
SMRiA8GBC1. Positions 1-330.

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
KOiK07404.
OMAiDKRFLYV.
OrthoDBiEOG615VK7.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMiSSF50974. SSF50974. 2 hits.

Sequencei

Sequence statusi: Complete.

A8GBC1-1 [UniParc]FASTAAdd to Basket

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MKQIVYVASP ESQQIHVWQL SDAGALELLQ TVEAPGQVQP MAIHPDRTHL    50
YVGVRPAFGI VSYRIEADGT LQQAGMAPLP GSPTHISTDL QGRYLFSASY 100
SGNCASVSPI GHDGVVVAPI QQIDGLTAPH SANIDPTNQL LLVPCLKEDR 150
IRLFNLDLQG ELTPHTQEAV TTASGAGPRH MAFHHNDKYA YCVNELDGTV 200
DVFAISENGG KYTLVQTLDI MPADFNGTRW AADIHITPNG RFLYTSDRTA 250
SILTIFSVSE DGSTLSVVGY HPTEEQPRGF NIDHSGRFVI SSGQKSGHIG 300
VYEIDQASGK LTTLARYPVG KGPMWVSILA K 331
Length:331
Mass (Da):35,802
Last modified:November 13, 2007 - v1
Checksum:i551F984B69D94F66
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000826 Genomic DNA. Translation: ABV40411.1.
RefSeqiWP_012005741.1. NC_009832.1.
YP_001477539.1. NC_009832.1.

Genome annotation databases

EnsemblBacteriaiABV40411; ABV40411; Spro_1307.
GeneIDi5605237.
KEGGispe:Spro_1307.
PATRICi32415310. VBISerPro44537_1340.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000826 Genomic DNA. Translation: ABV40411.1 .
RefSeqi WP_012005741.1. NC_009832.1.
YP_001477539.1. NC_009832.1.

3D structure databases

ProteinModelPortali A8GBC1.
SMRi A8GBC1. Positions 1-330.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 399741.Spro_1307.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABV40411 ; ABV40411 ; Spro_1307 .
GeneIDi 5605237.
KEGGi spe:Spro_1307.
PATRICi 32415310. VBISerPro44537_1340.

Phylogenomic databases

eggNOGi COG2706.
HOGENOMi HOG000257418.
KOi K07404.
OMAi DKRFLYV.
OrthoDBi EOG615VK7.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci SPRO399741:GI55-1357-MONOMER.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
HAMAPi MF_01605. 6P_gluconolactonase.
InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
Pfami PF10282. Lactonase. 1 hit.
[Graphical view ]
SUPFAMi SSF50974. SSF50974. 2 hits.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 568.

Entry informationi

Entry namei6PGL_SERP5
AccessioniPrimary (citable) accession number: A8GBC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: September 3, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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