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Protein

Adenine deaminase

Gene

ade

Organism
Serratia proteamaculans (strain 568)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciSPRO399741:GI55-1154-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:Spro_1116
OrganismiSerratia proteamaculans (strain 568)
Taxonomic identifieri399741 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia
Proteomesi
  • UP000007074 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 595595Adenine deaminasePRO_0000318549Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi399741.Spro_1116.

Structurei

3D structure databases

ProteinModelPortaliA8GAT0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiAGVTSDH.
OrthoDBiPOG091H00I8.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

A8GAT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTHCISTGE RQRAVKAALG QLPFDLLLTN AALIDMATGE VRNVDVGIVG
60 70 80 90 100
ALIASVHPCG TLTEALQTQD LAGAYLSPGL IDTHVHVESS HLPPERYAEI
110 120 130 140 150
VVAQGTTTIF WDPHELANVL GVAGVRYAVD ASRGLPLRVI CAAPSSVPST
160 170 180 190 200
PGLEMSGADF AGQEMETMLA WPEVGGVAEV MDMHGVLNGS ERMLEILNAG
210 220 230 240 250
LNSGKLIEGH ARGLSGADLQ AYLAAGVTSD HELTSGADAL EKLRAGLTLE
260 270 280 290 300
IRGSHPYLLP EIVAALKTLP HLSSQITVCT DDVPPDMLLE KGGIVALLNM
310 320 330 340 350
LIEQGLPATD VLRMATLNAA IRLQRNDLGL IAAGRVADLV VFDSLTQLRA
360 370 380 390 400
QQVYVAGKLT AQQGKMQKPL NANPNVAAPR DTLRLQPLAA GDFVLKVPAI
410 420 430 440 450
RHGKATLRHI KGARFTQWNE TTVEVRNGEV QIPQGFSLIW VQHRHGRHQA
460 470 480 490 500
TPQLALLEGW GELRGAIATS YSHDSHNLVV LGRDAADMAL AANALIASGG
510 520 530 540 550
GMALSQNGEI LAQVAMPIAG MLSDLPAAEL AQQFKNLRDL SARIADWEPP
560 570 580 590
YRVFKAIEGT CLACNAGPHL TDLGLTDGST RQIVDPLIAC WETPA
Length:595
Mass (Da):63,138
Last modified:November 13, 2007 - v1
Checksum:i914FFA6E2837E9A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA. Translation: ABV40220.1.
RefSeqiWP_012005556.1. NC_009832.1.

Genome annotation databases

EnsemblBacteriaiABV40220; ABV40220; Spro_1116.
KEGGispe:Spro_1116.
PATRICi32414900. VBISerPro44537_1147.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000826 Genomic DNA. Translation: ABV40220.1.
RefSeqiWP_012005556.1. NC_009832.1.

3D structure databases

ProteinModelPortaliA8GAT0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi399741.Spro_1116.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV40220; ABV40220; Spro_1116.
KEGGispe:Spro_1116.
PATRICi32414900. VBISerPro44537_1147.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiAGVTSDH.
OrthoDBiPOG091H00I8.

Enzyme and pathway databases

BioCyciSPRO399741:GI55-1154-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADEC_SERP5
AccessioniPrimary (citable) accession number: A8GAT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: September 7, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.