Reviewed, UniProtKB/Swiss-Prot A8G8T8 (SYK3_SERP5)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Ordered Locus Names:	Spro_0420

Organism

Serratia proteamaculans (strain 568) [Complete proteome] [HAMAP]

Taxonomic identifier

399741 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Serratia

Protein attributes

Sequence length	325 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 325	325	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_1000058329

Sequences

	Sequence		Length	Mass (Da)
	A8G8T8-1 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: A4232B21390E9E50	FASTA	325	36,679
	10 20 30 40 50 60 MSETASWQPS APIANLLKRA AILTEIRRFF ADRGVLEVET PTMSQATVTD IHLFPFQTRF 70 80 90 100 110 120 VGPGAADGLT LYMMTSPEYH MKRLLAAGSG PIYQMGRSFR NEEAGRHHNP EFTMLEWYRP 130 140 150 160 170 180 HYDMYRLMNE VDDLLQQVLD CDSAETLSYQ QAFLRHLDID PLSAEKAQLR EAAAKLDLSN 190 200 210 220 230 240 IADTEEDRDT LLQLLFTVGV EPHIGRDKPA FVYHFPASQA SLAEISTEDH RVAERFEVYF 250 260 270 280 290 300 KGIELANGFR ELTDSREQGQ RFAQDNRKRA ERGLPQHPID NNLLDALQHG MPECSGVALG 310 320 VDRLVMLALG AESLSEVLAF PVDRA

References

[1]

"Complete sequence of chromosome of Serratia proteamaculans 568." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E. , Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P. Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000826 Genomic DNA. Translation: ABV39528.1.
RefSeq	YP_001476656.1.
3D structure databases
SMR	A8G8T8. Positions 13-325.
ModBase	Search...
Protein-protein interaction databases
STRING	A8G8T8.
Genome annotation databases
GeneID	5602500.
GenomeReviews	Gene locus Spro_0420 in contig CP000826_GR.
KEGG	spe:Spro_0420.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2269.
HOGENOM	HBG631383.
OMA	PGNEAHL.
Family and domain databases
HAMAP	MF_00174. Put_Lys_tRNA_synth. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-dom. IPR004525. Lys-tRNA-synth-rel. IPR018149. Lys-tRNA-synth_II_C. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
PRINTS	PR00982. TRNASYNTHLYS.
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_SERP5

Accession

Primary (citable) accession number: A8G8T8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	February 9, 2010
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)