Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot A8G786 (HEM6_PROM2)

Last modified June 16, 2009. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: P9215_18541
OrganismProchlorococcus marinus (strain MIT 9215) [Complete proteome] [HAMAP]
Taxonomic identifier93060 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Hide | Top

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

Hide | Top

Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 342342Coproporphyrinogen-III oxidase, aerobic
PRO_1000059707

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
A8G786-1 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: BAFA20A5522F5A2E

FASTA34239,586
        10         20         30         40         50         60 
MFKEPPKNSR EKTKNLLLTL QNKICSGLEN IDEKGKFIEE SWIRDEGGGG RSRVLKNGSI 

        70         80         90        100        110        120 
FEQAGVNFSE VQGKELPQSI VSQRPEAKGH EWFATGTSMV LHPKNPYIPT VHLNYRYFEA 

       130        140        150        160        170        180 
GPVWWFGGGA DLTPFYPYLS DVRNFHNEHK KACEKVDNDL HKVFKPWCDE YFFLKHRNES 

       190        200        210        220        230        240 
RGIGGIFYDY QDGSGNIYRG NNQNGEASKA SQSISKSNLN WDNLFSLAEN CGQAFLPSYL 

       250        260        270        280        290        300 
PIIEKRASQT YSSREREFQL YRRGRYVEFN LVWDRGTIFG LQTNGRTESI LMSLPPLARW 

       310        320        330        340 
EYGYKAKKGS REEFLTSIFT KPQDWLDDKD LEKFCLENNI FD

« Hide

Hide | Top

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Hide | Top

Cross-references

Sequence databases

CP000825 Genomic DNA. Translation: ABV51467.1.
RefSeqYP_001485053.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5615929.
GenomeReviewsGene locus P9215_18541 in contig CP000825_GR.
KEGGpmh:P9215_18541.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAA8G786. VFKPWCD.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameHEM6_PROM2
AccessionPrimary (citable) accession number: A8G786
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: June 16, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents