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A8G731

- A8G731_PROM2

UniProt

A8G731 - A8G731_PROM2

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Protein

Alanine racemase

Gene

alr

Organism
Prochlorococcus marinus (strain MIT 9215)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei59 – 591Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei158 – 1581SubstrateUniRule annotation
Active sitei291 – 2911Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei339 – 3391Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPMAR93060:GI08-1857-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:P9215_17991Imported
OrganismiProchlorococcus marinus (strain MIT 9215)Imported
Taxonomic identifieri93060 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002014: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei59 – 591N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi93060.P9215_17991.

Structurei

3D structure databases

ProteinModelPortaliA8G731.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiKSNTIPW.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8G731-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQIRQINKRF NFDKYQTFNQ DINPKQRAWI EVKGKALEIN VRQLRTKLSK
60 70 80 90 100
NCQFMAVVKA DGYGHDAKVV SDYAIRGGAS QLGVATLKEG IKLRSFGVKK
110 120 130 140 150
PILILGNLYT KKDLIISFKN DLMPTISSIR ECFICNNIGK HFGLKFSLHL
160 170 180 190 200
KVDTGMSRLG FESNKFVQQF EKIKSLENIS IDGIYSHLSS ADAENALDPQ
210 220 230 240 250
SITQLQRLKF NQLLKQINLD RNNEIKIHLA NSAGMLLNKD FHFNMVRVGL
260 270 280 290 300
SMYGYSPLAK IDKNLLLKPA LFLKVKVAFI RIIEPGVSVS YGGKFVSSRK
310 320 330 340 350
TKLAVLSIGY ADGVPRNLSG KINVIHNNKL YPQVGSITMD QMMVDITGSN
360 370 380 390
EIRIGSTMVL LGSDGDKTIS PLEWATKSNT IPWEILCSFK NRLPRVQVD
Length:399
Mass (Da):44,845
Last modified:November 13, 2007 - v1
Checksum:i1CD764BE2BFA8866
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000825 Genomic DNA. Translation: ABV51412.1.
RefSeqiWP_012008425.1. NC_009840.1.
YP_001484998.1. NC_009840.1.

Genome annotation databases

EnsemblBacteriaiABV51412; ABV51412; P9215_17991.
GeneIDi5616218.
KEGGipmh:P9215_17991.
PATRICi22993200. VBIProMar119824_1858.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000825 Genomic DNA. Translation: ABV51412.1 .
RefSeqi WP_012008425.1. NC_009840.1.
YP_001484998.1. NC_009840.1.

3D structure databases

ProteinModelPortali A8G731.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 93060.P9215_17991.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABV51412 ; ABV51412 ; P9215_17991 .
GeneIDi 5616218.
KEGGi pmh:P9215_17991.
PATRICi 22993200. VBIProMar119824_1858.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi KSNTIPW.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci PMAR93060:GI08-1857-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MIT 9215Imported.

Entry informationi

Entry nameiA8G731_PROM2
AccessioniPrimary (citable) accession number: A8G731
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: November 26, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3