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A8G731 (A8G731_PROM2) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 RuleBase RU004247

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site591Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2911Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1581Substrate By similarity HAMAP-Rule MF_01201
Binding site3391Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue591N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
A8G731 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 1CD764BE2BFA8866

FASTA39944,845
        10         20         30         40         50         60 
MQIRQINKRF NFDKYQTFNQ DINPKQRAWI EVKGKALEIN VRQLRTKLSK NCQFMAVVKA 

        70         80         90        100        110        120 
DGYGHDAKVV SDYAIRGGAS QLGVATLKEG IKLRSFGVKK PILILGNLYT KKDLIISFKN 

       130        140        150        160        170        180 
DLMPTISSIR ECFICNNIGK HFGLKFSLHL KVDTGMSRLG FESNKFVQQF EKIKSLENIS 

       190        200        210        220        230        240 
IDGIYSHLSS ADAENALDPQ SITQLQRLKF NQLLKQINLD RNNEIKIHLA NSAGMLLNKD 

       250        260        270        280        290        300 
FHFNMVRVGL SMYGYSPLAK IDKNLLLKPA LFLKVKVAFI RIIEPGVSVS YGGKFVSSRK 

       310        320        330        340        350        360 
TKLAVLSIGY ADGVPRNLSG KINVIHNNKL YPQVGSITMD QMMVDITGSN EIRIGSTMVL 

       370        380        390 
LGSDGDKTIS PLEWATKSNT IPWEILCSFK NRLPRVQVD 

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9215 EMBL ABV51412.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000825 Genomic DNA. Translation: ABV51412.1.
RefSeqYP_001484998.1. NC_009840.1.

3D structure databases

ProteinModelPortalA8G731.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING93060.P9215_17991.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV51412; ABV51412; P9215_17991.
GeneID5616218.
KEGGpmh:P9215_17991.
PATRIC22993200. VBIProMar119824_1858.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAKSNTIPW.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycPMAR93060:GI08-1857-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8G731_PROM2
AccessionPrimary (citable) accession number: A8G731
Entry history
Integrated into UniProtKB/TrEMBL: November 13, 2007
Last sequence update: November 13, 2007
Last modified: July 9, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)