A8G4K7 (URE3_PROM2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease subunit gamma
EC=3.5.1.5

Alternative name(s):
Urea amidohydrolase subunit gamma

Gene names

Name:	ureA
Ordered Locus Names:	P9215_09231

Organism

Prochlorococcus marinus (strain MIT 9215) [Complete proteome] [HAMAP]

Taxonomic identifier

93060 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	100 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Urea + H2O = CO2 + 2 NH3. HAMAP MF_00739
Pathway	Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP MF_00739
Subunit structure	Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00739.
Sequence similarities	Belongs to the urease gamma subunit family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	urea metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro urease activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 100	100	Urease subunit gamma HAMAP MF_00739		PRO_1000062145

Sequences

	Sequence		Length	Mass (Da)
	A8G4K7 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 840698AF35410922	FASTA	100	11,184
	10 20 30 40 50 60 MHLSPQEKDK LLIFSAALLA ERRLDRGLKL NYPETIAFLS FQVLEGARDG KSVSQLMSEG 70 80 90 100 TTWLTKSQVM EGIPEMVDEV QIEAVFPDGT KLVTIHNPIN

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MIT 9215.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000825 Genomic DNA. Translation: ABV50538.1.
RefSeq	YP_001484124.1. NC_009840.1.
3D structure databases
ProteinModelPortal	A8G4K7.
SMR	A8G4K7. Positions 1-99.
ModBase	Search...
Protein-protein interaction databases
STRING	A8G4K7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5615773.
GenomeReviews	Gene locus P9215_09231 in contig CP000825_GR.
KEGG	pmh:P9215_09231.
PATRIC	22991342. VBIProMar119824_0945.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0831.
HOGENOM	HBG286300.
OMA	HVITRDQ.
PhylomeDB	A8G4K7.
ProtClustDB	PRK13241.
Enzyme and pathway databases
BioCyc	PMAR93060:P9215_09231-MONOMER.
Family and domain databases
HAMAP	MF_00739. Urease_gamma. [Tree]
InterPro	IPR002026. Urease_gamma/gamma-beta_su. IPR012010. Urease_gamma_su. [Graphical view]
Gene3D	G3DSA:3.30.280.10. Urease_gamma_reg. 1 hit.
KO	K01430.
Pfam	PF00547. Urease_gamma. 1 hit. [Graphical view]
PIRSF	PIRSF001223. Urease_gamma. 1 hit.
ProDom	PD002319. Urease_gamma_reg. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF54111. Urease_gamma_reg. 1 hit.
TIGRFAMs	TIGR00193. Urease_gam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

URE3_PROM2

Accession

Primary (citable) accession number: A8G4K7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program