A8G3D1 (MQO_PROM2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	P9215_04961

Organism

Prochlorococcus marinus (strain MIT 9215) [Complete proteome] [HAMAP]

Taxonomic identifier

93060 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	498 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 498	498	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000325506

Sequences

	Sequence		Length	Mass (Da)
	A8G3D1 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: BFA6A348974476D3	FASTA	498	55,530
	10 20 30 40 50 60 MTSSKNPTND NSYFDAVLVG GGIMSSTLAL LISEVLPDIK FLIIEKLNAP GSESTGAFNN 70 80 90 100 110 120 AGTGHAANCE LNYTPLDEKG NLKIDKALSI NRSFETSMSL WASLYEAGKI DIKKFLKFIP 130 140 150 160 170 180 HISFVSGQDN ISFLKKRFQK MTENPEFIDM EFSTSFDEIS SWAPLITKDR NPSTQIAATR 190 200 210 220 230 240 IGRGTDINFE ALTKEYLSLV SLNKNVEIRY KTELIDLMKI DKKQWELEIS SEGRKTSIRT 250 260 270 280 290 300 GYVFLGAGGK TINYLQKSKI PEAKSYGGFP VSGKWLICEK KDLTEKHNSK VYGKADIGSP 310 320 330 340 350 360 PMSVPHLDTR WIDNKKLLLY GPFAGFTTKF LKQSSYFDLF SSIKKNNIFS MLDVGFKNND 370 380 390 400 410 420 LINYLISQSL KSHNSRVENL KNMMPSANPS DWYLKNAGQR VQIIKKTEGG GSLKFGTEIV 430 440 450 460 470 480 NSSDGSLSAL LGASPGASTA VSIMVEVLEK SVLFLNDKHN LKKKINDLIY PERTASQKNS 490 TFIKEIKKRN NSIFGFHP

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MIT 9215.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000825 Genomic DNA. Translation: ABV50112.1.
RefSeq	YP_001483698.1. NC_009840.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A8G3D1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5614961.
GenomeReviews	Gene locus P9215_04961 in contig CP000825_GR.
KEGG	pmh:P9215_04961.
PATRIC	22990440. VBIProMar119824_0498.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	KKWVPLM.
PhylomeDB	A8G3D1.
ProtClustDB	PRK05257.
Enzyme and pathway databases
BioCyc	PMAR93060:P9215_04961-MONOMER.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MQO_PROM2

Accession

Primary (citable) accession number: A8G3D1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	November 13, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program