A8G2U3 (A8G2U3_PROM2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Name:	fabI EMBL ABV49924.1
Ordered Locus Names:	P9215_03071

Organism

Prochlorococcus marinus (strain MIT 9215) [Complete proteome] [HAMAP]

Taxonomic identifier

93060 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL ABV49924.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	159	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	A8G2U3 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 598B571E2A34BCFF	FASTA	260	27,772
	10 20 30 40 50 60 MLLNLTGKKI LVTGIANNRS IAWGIAQQLS KAGAELGITY LPDDKGRFES KVRELTEPLN 70 80 90 100 110 120 PSLFLPLDVQ NPAQIEEIFK NIKNNWVQID GLVHCLAFAG RDELIGDYSA TTSEGFDRAL 130 140 150 160 170 180 NISAYSLAPL CKAAKPLFSD GAGVVSLTYL GSERAIPNYN VMGVAKAALE ASVRYLSAEL 190 200 210 220 230 240 GPEKQVRVNA ISAGPIRTLA SSAIGGILDM IHNVEEKAPL RRTVTQTEVG NTAAFLLSDL 250 260 SSGISGQTIY VDAGYCINGM

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000825 Genomic DNA. Translation: ABV49924.1.
RefSeq	YP_001483510.1. NC_009840.1.
3D structure databases
ProteinModelPortal	A8G2U3.
ModBase	Search...
Protein-protein interaction databases
STRING	A8G2U3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5615246.
GenomeReviews	Gene locus P9215_03071 in contig CP000825_GR.
KEGG	pmh:P9215_03071.
PATRIC	22990028. VBIProMar119824_0303.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0623.
HOGENOM	HBG750976.
OMA	MILKWNE.
PhylomeDB	A8G2U3.
ProtClustDB	PRK07370.
Enzyme and pathway databases
BioCyc	PMAR93060:P9215_03071-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00208.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

A8G2U3_PROM2

Accession

Primary (citable) accession number: A8G2U3

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)