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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Prochlorococcus marinus (strain MIT 9215)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:P9215_02731
OrganismiProchlorococcus marinus (strain MIT 9215)
Taxonomic identifieri93060 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002014 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000575531 – 200Peptidyl-tRNA hydrolaseAdd BLAST200

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi93060.P9215_02731.

Structurei

3D structure databases

ProteinModelPortaliA8G2Q9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD. Bacteria.
COG0193. LUCA.
HOGENOMiHOG000004797.
KOiK01056.
OMAiRFYKILP.
OrthoDBiPOG091H02CU.

Family and domain databases

CDDicd00462. PTH. 1 hit.
Gene3Di3.40.50.1470. 1 hit.
HAMAPiMF_00083. Pept_tRNA_hydro_bact. 1 hit.
InterProiIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERiPTHR17224. PTHR17224. 1 hit.
PfamiPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53178. SSF53178. 1 hit.
TIGRFAMsiTIGR00447. pth. 1 hit.
PROSITEiPS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8G2Q9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEIYLIGLG NPGKKFLNSR HNIGFLLLEY FSKKYNSNFL FKDKLKSSYS
60 70 80 90 100
EFQIDNSSYR LFLPNTFMNN SGYAVRAIVD WYKINLDQIF IIVDDKDLPL
110 120 130 140 150
GKIRFRRKGS SGGHNGLKSI IEQLQTQKFK RIRIGIGSPP PIKGEKNFNT
160 170 180 190 200
ISHVLGNISL EEKSILDKVF RRVIESLEKL NTKKEEYIIN ELNSFDKDQH
Length:200
Mass (Da):23,256
Last modified:November 13, 2007 - v1
Checksum:i08237D31BE47BABC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000825 Genomic DNA. Translation: ABV49890.1.
RefSeqiWP_012007051.1. NC_009840.1.

Genome annotation databases

EnsemblBacteriaiABV49890; ABV49890; P9215_02731.
KEGGipmh:P9215_02731.
PATRICi22989958. VBIProMar119824_0270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000825 Genomic DNA. Translation: ABV49890.1.
RefSeqiWP_012007051.1. NC_009840.1.

3D structure databases

ProteinModelPortaliA8G2Q9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi93060.P9215_02731.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV49890; ABV49890; P9215_02731.
KEGGipmh:P9215_02731.
PATRICi22989958. VBIProMar119824_0270.

Phylogenomic databases

eggNOGiENOG4108ZPD. Bacteria.
COG0193. LUCA.
HOGENOMiHOG000004797.
KOiK01056.
OMAiRFYKILP.
OrthoDBiPOG091H02CU.

Family and domain databases

CDDicd00462. PTH. 1 hit.
Gene3Di3.40.50.1470. 1 hit.
HAMAPiMF_00083. Pept_tRNA_hydro_bact. 1 hit.
InterProiIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERiPTHR17224. PTHR17224. 1 hit.
PfamiPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53178. SSF53178. 1 hit.
TIGRFAMsiTIGR00447. pth. 1 hit.
PROSITEiPS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPTH_PROM2
AccessioniPrimary (citable) accession number: A8G2Q9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 13, 2007
Last modified: November 2, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.