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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Shewanella sediminis (strain HAW-EB3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciSSED425104:GH7Q-4580-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:Ssed_4429
OrganismiShewanella sediminis (strain HAW-EB3)
Taxonomic identifieri425104 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000002015 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 404404Ribosomal RNA large subunit methyltransferase FPRO_0000349961Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi425104.Ssed_4429.

Structurei

3D structure databases

ProteinModelPortaliA8G1Q8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 3 hits.
PfamiPF05971. Methyltransf_10. 2 hits.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.

Sequencei

Sequence statusi: Complete.

A8G1Q8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKHSQKQNR QKQTTQKQTR RKKPAGKLKA KSEAKLDTRG KPETTEKKGL
60 70 80 90 100
HERNLHRDGY DFEQLIEASP ALKPYVRPNP YGNLSIDFAD PLAVKALNLA
110 120 130 140 150
LLQLHYRIEY WDIPAGFLCP PIPGRVDYLH YIADLLAGID SDTVGDKAEE
160 170 180 190 200
QVEEIGTRQN VPYASKPESS APKQRYKSQK RMKINALDIG TGANGIYPIL
210 220 230 240 250
GIQAYGWRFV ASDVDPLSIE NVNRIVGQNK ALQGKLKTRL QTDHQKVFHG
260 270 280 290 300
IIQADDRFDI TLCNPPFHAS LSEASEGSLR KVKNLAANRA AKGHKPEPAA
310 320 330 340 350
SKAKPDANEL NFGGQKAELW CEGGEKQFLA NMIRESKDFA TQCLWFTSLV
360 370 380 390 400
SKKENLQPCY AALEKVGAVT VKTIDMAQGN KLTRVLAWSY LTPKQQALWA

KYRS
Length:404
Mass (Da):45,236
Last modified:November 13, 2007 - v1
Checksum:iBF7474AFFB54E1C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000821 Genomic DNA. Translation: ABV39031.1.
RefSeqiWP_012144758.1. NC_009831.1.

Genome annotation databases

EnsemblBacteriaiABV39031; ABV39031; Ssed_4429.
KEGGisse:Ssed_4429.
PATRICi23566848. VBISheSed62411_4707.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000821 Genomic DNA. Translation: ABV39031.1.
RefSeqiWP_012144758.1. NC_009831.1.

3D structure databases

ProteinModelPortaliA8G1Q8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi425104.Ssed_4429.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV39031; ABV39031; Ssed_4429.
KEGGisse:Ssed_4429.
PATRICi23566848. VBISheSed62411_4707.

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Enzyme and pathway databases

BioCyciSSED425104:GH7Q-4580-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 3 hits.
PfamiPF05971. Methyltransf_10. 2 hits.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HAW-EB3.

Entry informationi

Entry nameiRLMF_SHESH
AccessioniPrimary (citable) accession number: A8G1Q8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: November 13, 2007
Last modified: November 11, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.