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A8FZR5 (COBT_SHESH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Short name=NN:DBI PRT
EC=2.4.2.21
Alternative name(s):
N(1)-alpha-phosphoribosyltransferase
Gene names
Name:cobT
Ordered Locus Names:Ssed_3734
OrganismShewanella sediminis (strain HAW-EB3) [Complete proteome] [HAMAP]
Taxonomic identifier425104 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB) By similarity. HAMAP-Rule MF_00230

Catalytic activity

Beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole = nicotinate + alpha-ribazole 5'-phosphate. HAMAP-Rule MF_00230

Pathway

Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2. HAMAP-Rule MF_00230

Sequence similarities

Belongs to the CobT family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 342342Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase HAMAP-Rule MF_00230
PRO_1000078251

Sites

Active site3111Proton acceptor By similarity

Sequences

Sequence LengthMass (Da)Tools
A8FZR5 [UniParc].

Last modified November 13, 2007. Version 1.
Checksum: 692789F995633F1B

FASTA34236,215
        10         20         30         40         50         60 
MFNISPANHE FDDEIQSKID NKTKPLGALG ELENLAKQLA LVLGKDKPEI INPKLLVFAA 

        70         80         90        100        110        120 
DHGIASSGVS IAPSEVTTQM VMNFVAGGAA INVFCRQVGL DMEVIDCGIL QPLEGVEGVI 

       130        140        150        160        170        180 
DQRLGAGTGA IHKQAAMTLG AVKQGLEMAR TRIELHHQQG CNLIALGEMG IGNTSSAAAI 

       190        200        210        220        230        240 
MATVMGMKGV DCVGRGTGID AATLKRKQML VEQALHIHEA ELTDPYNILA CLGGFEIVQM 

       250        260        270        280        290        300 
TGAMLAAAER NMLVIVDGFI ATAAAMVAVQ INANVRDYMI FGHQSDERGH CLMMEHLQAR 

       310        320        330        340 
PLLRLGMRLG EGSGAVLALP LIRAAAGFYN EMASFSDAGI EI 

« Hide

References

[1]"Complete sequence of Shewanella sediminis HAW-EB3."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Zhao J.-S., Richardson P.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HAW-EB3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000821 Genomic DNA. Translation: ABV38338.1.
RefSeqYP_001475466.1. NC_009831.1.

3D structure databases

ProteinModelPortalA8FZR5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING425104.Ssed_3734.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABV38338; ABV38338; Ssed_3734.
GeneID5614185.
KEGGsse:Ssed_3734.
PATRIC23565320. VBISheSed62411_3960.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2038.
HOGENOMHOG000263500.
KOK00768.
OMAFIGGEMG.
OrthoDBEOG6HF61K.
ProtClustDBPRK00105.

Enzyme and pathway databases

BioCycSSED425104:GH7Q-3868-MONOMER.
UniPathwayUPA00061; UER00516.

Family and domain databases

Gene3D1.10.1610.10. 1 hit.
HAMAPMF_00230. CobT.
InterProIPR003200. Nict_dMeBzImd_PRibTrfase-like.
IPR023195. Nict_dMeBzImd_PRibTrfase_N.
IPR017846. Nict_dMeBzImd_PRibTrfase_pro.
[Graphical view]
PfamPF02277. DBI_PRT. 1 hit.
[Graphical view]
SUPFAMSSF52733. SSF52733. 1 hit.
TIGRFAMsTIGR03160. cobT_DBIPRT. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOBT_SHESH
AccessionPrimary (citable) accession number: A8FZR5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 13, 2007
Last modified: April 16, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways