A8FZ55 (A8FZ55_SHESH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Adenosine deaminase HAMAP MF_00540
EC=3.5.4.4 HAMAP MF_00540

Alternative name(s):
Adenosine aminohydrolase HAMAP MF_00540

Gene names

Name:	add HAMAP MF_00540
Ordered Locus Names:	Ssed_3524

Organism

Shewanella sediminis (strain HAW-EB3) [Complete proteome] [HAMAP] EMBL ABV38128.1

Taxonomic identifier

425104 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenosine + H2O = inosine + NH3. HAMAP MF_00540
Cofactor	Binds 1 zinc ion per subunit By similarity. HAMAP MF_00540
Sequence similarities	Belongs to the adenosine and AMP deaminases family. Adenosine deaminase subfamily. HAMAP MF_00540

Ontologies

Keywords
Biological process	Nucleotide metabolism HAMAP MF_00540
Ligand	Metal-binding HAMAP MF_00540 Zinc HAMAP MF_00540
Molecular function	Hydrolase HAMAP MF_00540 EMBL ABV38128.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine ribonucleoside monophosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	adenosine deaminase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	200	1	Proton donor By similarity HAMAP MF_00540
	Metal binding	12	1	Zinc; catalytic By similarity HAMAP MF_00540
	Metal binding	14	1	Zinc; catalytic By similarity HAMAP MF_00540
	Metal binding	197	1	Zinc; catalytic By similarity HAMAP MF_00540
	Metal binding	278	1	Zinc; catalytic By similarity HAMAP MF_00540
	Binding site	14	1	Substrate By similarity HAMAP MF_00540
	Binding site	16	1	Substrate By similarity HAMAP MF_00540
	Binding site	170	1	Substrate; via amide nitrogen and carbonyl oxygen By similarity HAMAP MF_00540
	Site	221	1	Important for catalytic activity By similarity HAMAP MF_00540

Sequences

	Sequence		Length	Mass (Da)
	A8FZ55 [UniParc]. Last modified November 13, 2007. Version 1. Checksum: 56423F946E0BF1CB	FASTA	331	37,351
	10 20 30 40 50 60 MNYFNLPKID LHCHLDGSVR PQTIIDLAQE QSIPLPSQDI NEINSLMIAP ETCQNLEEYL 70 80 90 100 110 120 MRFDLPLSVM QTEAGIERIS FELFEDAAKE NVKYFEVRFG PQLHQQQGLS FKQIISSVVK 130 140 150 160 170 180 GMQRAEAMYD IRGNYILSIL RTFPKDNINA VIDAGAEFLG KGVAAFDLAG AELPGFCHEF 190 200 210 220 230 240 IPYAKYAKEK GYHITIHAGE QGVGQNVYDA VSLLNAERVG HGIHITGHQG AYDLVKQHNI 250 260 270 280 290 300 GLETCPSSNI QTKAVDKLSE HPVKAFYQDN LPITINTDNR TVSNTTMTDE VRKVMEEFNL 310 320 330 SREDYFNIYK ISIEQAFASD EVKQHLMQFA E

References

[1]

"Complete sequence of Shewanella sediminis HAW-EB3." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Zhao J.-S., Richardson P. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HAW-EB3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000821 Genomic DNA. Translation: ABV38128.1.
RefSeq	YP_001475256.1. NC_009831.1.
3D structure databases
ProteinModelPortal	A8FZ55.
ModBase	Search...
Protein-protein interaction databases
STRING	A8FZ55.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5612143.
GenomeReviews	Gene locus Ssed_3524 in contig CP000821_GR.
KEGG	sse:Ssed_3524.
NMPDR	fig|425104.3.peg.3122.
PATRIC	23564874. VBISheSed62411_3738.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1816.
HOGENOM	HBG630382.
OMA	PYYMAMN.
ProtClustDB	PRK09358.
Enzyme and pathway databases
BioCyc	SSED425104:SSED_3524-MONOMER.
Family and domain databases
HAMAP	MF_00540. A_deaminase. [Tree]
InterPro	IPR001365. A/AMP_deaminase_dom. IPR006330. A_deaminase. [Graphical view]
KO	K01488.
PANTHER	PTHR11409:SF21. PTHR11409:SF21. 1 hit.
Pfam	PF00962. A_deaminase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01430. Aden_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8FZ55_SHESH

Accession

Primary (citable) accession number: A8FZ55

Entry history

Integrated into UniProtKB/TrEMBL:	November 13, 2007
Last sequence update:	November 13, 2007
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)